نتایج جستجو برای: metalloprotein

تعداد نتایج: 408  

Journal: :Advanced Healthcare Materials 2023

Hybrid Nanoenzymes In article 2300385 by Xing-Can Shen and co-workers, a bioinspired metalloprotein-like hybrid nanozyme (FeS@GOx) is designed incorporating the FeS as brand-new cofactors within natural GOx protein scaffolds, providing feasible H2S gas amplified ROS cascade strategy for precise efficient tumor chemodynamic immunotherapy.

Journal: :Analytical and bioanalytical chemistry 2006
Igor A Kaltashov Mingxuan Zhang Stephen J Eyles Rinat R Abzalimov

Electrospray ionization mass spectrometry (ESI MS) has emerged recently as a powerful tool for analyzing many structural and behavioral aspects of metalloproteins in great detail. In this review we discuss recent developments in the field, placing particular emphasis on the unique features of ESI MS that lend themselves to metalloprotein characterization at a variety of levels. Direct mass meas...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1979
L W Scheibel A Adler W Trager

Plasmodium falciparum in culture grows optimally at 3% oxygen. Oxygen levels down to 0.5% still support growth, but anaerobic conditions do not. These findings, and the absence of the Krebs cycle in Plasmodium, suggested that in this organism oxygen may not function in electron transport but rather may act through metalloprotein oxygenases. Tetraethylthiuram disulfide (Antabuse, disulfiram) and...

Journal: :Proceedings of the National Academy of Sciences 2003

Journal: :Genome research 2011
Wuxian Shi Marco Punta Jen Bohon J Michael Sauder Rhijuta D'Mello Mike Sullivan John Toomey Don Abel Marco Lippi Andrea Passerini Paolo Frasconi Stephen K Burley Burkhard Rost Mark R Chance

High-throughput X-ray absorption spectroscopy was used to measure transition metal content based on quantitative detection of X-ray fluorescence signals for 3879 purified proteins from several hundred different protein families generated by the New York SGX Research Center for Structural Genomics. Approximately 9% of the proteins analyzed showed the presence of transition metal atoms (Zn, Cu, N...

Journal: :The Journal of biological chemistry 1999
V W Yang S R LaBrenz L C Rosenberg D McQuillan M Höök

Decorin is ubiquitously distributed in the extracellular matrix of mammals and a member of the proteoglycan family characterized by a core protein dominated by leucine-rich repeat motifs. We show here that decorin extracted from bovine tissues under denaturing conditions or produced in recombinant "native" form by cultured mammalian cells has a high affinity for Zn2+ as demonstrated by equilibr...

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