Objective: To assess neuromuscular transmission (NMT) in patients with Meniere's disease (MD), in which the precise etiology is unknown and a channelopathy hypothesis has been proposed Methods: Single fiber electromyography (SFEMG) during voluntary contraction of the extansor digitorum communis muscle, nerve conduction studies of upper and lower extremities and concentric needle electromyograph...

Meniere disease (MD) is a heterogeneous clinical condition characterized by sensorineural hearing loss, episodic vestibular symptoms, and tinnitus associated with several comorbidities, such as migraine or autoimmune disorders (AD). The frequency of bilateral involvement may range from 5 to 50%, and it depends on the duration of the disease. We have performed a two-step cluster analysis in 398 ...

BACKGROUND Tumarkin falls are sudden drop-attack falls that occur in a subset of patients with Meniere syndrome (endolymphatic hydrops), an inner ear disorder characterized by vertigo spells and hearing loss. OBJECTIVE To describe the clinical features and quantitative audiovestibular testing results in a case series of patients with Tumarkin falls, episodic vertigo, and normal hearing. SET...

background: meniere’s disease (md) is a chronic illness defined as an idiopathic syndrome of endolymphatic hydrops. benign paroxysmal positional vertigo (bppv) is a balance disorder and can be the sequel of diverse inner ear impairments. objectives: the purpose of this study was to investigate the prevalence of bppv in md patients. materials and methods: all patients with definite or probable m...

35 patients with unilateral sensorineural impairment and hearing levels within the normal range in the opposite ears were investigated by bilateral transtympanic electrocochleography (tiecog). only 19 patients (54%) satisfied the criteria for meniere's disease and 16 patients (46%) showed sensorineural impairment due to other etiologies. clinical studies have focused exclusively on the a m...

Corticosteroid administration has been widely used as the empirical treatment for various inner ear diseases such as sudden sensorineural hearing loss (SNHL), Meniere disease, and autoimmune-induced hearing loss for a long time. After Sakata et al. [1] first tried intratympanic (IT) steroid injection to control Meniere disease, IT steroid injection treatment has been used as an alternative opti...

Dizziness accounts for an estimated 5 percent of primary care clinic visits. The patient history can generally classify dizziness into one of four categories: vertigo, disequilibrium, presyncope, or lightheadedness. The main causes of vertigo are benign paroxysmal positional vertigo, Meniere disease, vestibular neuritis, and labyrinthitis. Many medications can cause presyncope, and regimens sho...

OBJECTIVES Physiological studies with experimental models of endolymphatic hydrops in Meniere's disease demonstrate some pressure changes at the level of round and oval window. Interestingly, conductive type hearing loss was observed in some patients during Meniere episodes. A close auditory follow-up of these patients may provide a better understanding of hydrodynamic changes of the hydrops an...