Proteus syndrome is a rare congenital condition with various clinical features such as hemihypertrophy, macrodactyly, subcutaneous masses, brain-like hyperplasia of the soles and/or palms, epidermal naevi and scoliosis with other mesodermal malformations. Multifocal overgrowth can affect various tissues causing severe functional and cosmetic disability, but intellectual and language development...

S., a Hindu girl, aged 10 years, of the village Saraiyan, in Ghazipnr district, was admitted into the hospital with abnormal enlargement of the right middle finger. She came to the hospital for its removal, as she had been feeling its weight. It is seven and a half inches in length and seven and a half inches in diameter at its thickest part. The left middle finger is three inches in length and...

We present a case of a 3½-year-old girl diagnosed as Proteus syndrome with severe cosmetic disfigurement-macrodactyly, hemi-hypertrophy of the face and limbs, megalencephaly, lymph edema of both hands and feet along with severe global developmental delay. She was found to have severe recalcitrant epilepsy and also primary hypothyroidism; the association of which is not mentioned in the previous...

fibrolipomatous hamartoma of nerve (neural fibrolipoma) is a tumor-like lipomatous process principally involving young persons. the median nerve is most commonly affected. the lesion is characterized by a soft slowly growing mass surrounding and infiltrating major nerves and their branches. it may cause symptoms of compression neuropathy and is associated with macrodactyly in one third of cases...

To cite: Iyengar KP, Matar HE, Suraliwala K. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016218043 DESCRIPTION Macrodactyly is a descriptive term used for a rare anomaly of disproportionately large digit noted at birth or that develops within the first years of life. The soft tissue and skeletal elements are diffusely enlarged in the affected digit or digits....