gam mutants of phage lambda carrying long palindromes fail to form plaques on wild-type Escherichia coli but do grow on strains that are mutant in the sbcC gene. gam + lambda carrying the same palindrome grow on both hosts and on a host deleted for the recB, C and D genes. These results suggest that the Gam protein of lambda, known to interact also with E. coli's recBCD protein, can interact wi...

In pre-B cells, immunoglobulin mu (Ig mu) is associated with pre-B cell-specific proteins to form a multimeric complex that is found on the cell surface. One of these proteins is encoded by the three exon Ig lambda-like gene 14.1, whose expression is restricted to pre-B cells and occurs from an unrearranged gene. A comparison of the 14.1 gene structure to the seven-gene human Ig lambda locus re...

Transgenic mice that carry a lambda 2 transgene under the control of the V lambda 2 promoter and the E lambda 2-4 enhancer (lambda 2E lambda mice) are described. A high proportion of B cells in the spleen and the bone marrow express the lambda transgene on the cell membrane. lambda 2 protein is synthesized by all lambda 2E lambda-derived spleen B-cell hybridomas that have retained the transgene...

A U2 small nuclear RNA-associated protein, designated B'', was recently identified as the target antigen for autoimmune sera from certain patients with systemic lupus erythematosus and other rheumatic diseases. Such antibodies enabled us to isolate cDNA clone lambda HB''-1 from a phage lambda gt11 expression library. This clone appeared to code for the B'' protein as established by in vitro tra...

To define the events necessary for the establishment and maintenance of repression in a lambda-infected cell, we have studied the requirements for efficient synthesis of the cI protein ("lambda-repressor"). Three classes of lambda mutants defective in the establishment of repression are also defective in the appearance of cI protein activity at the normal time. Two of these mutational classes (...

BACKGROUND Consistent progress in the development of bacteriophage lambda display platform as an alternative to filamentous phage display system was achieved in the recent years. The lambda phage has been engineered to display efficiently multiple copies of peptides or even large protein domains providing a powerful tool for screening libraries of peptides, proteins and cDNA. RESULTS In the p...

‎in this paper‎, ‎we study a class of boundary value problem‎ ‎involving the p-laplacian oprator and singular nonlinearities‎. ‎we‎ ‎analyze the existence a critical parameter $lambda^{ast}$ such‎ ‎that the problem has least one solution for‎ ‎$lambdain(0,lambda^{ast})$ and no solution for‎ ‎$lambda>lambda^{ast}.$ we find lower bounds of critical‎ ‎parameter $lambda^{ast}$‎. ‎we use the method ...

Lambda-cyhalothrin (trade name Karate) is a pyrethroid insecticide, widely used to control insect pests in agriculture, public health, and homes and gardens. In the present study, an attempt has been made to study the effect of lambda-cyhalothrin on protein content of different tissues like liver, muscle and brain of the edible fish Etroplus suratensis (Bloch). The E. suratensis fishes were exp...

In this paper, we investigate the existence of positive solutions for the ellipticequation $Delta^{2},u+c(x)u = lambda f(u)$ on a bounded smooth domain $Omega$ of $R^{n}$, $ngeq2$, with Navier boundary conditions. We show that there exists an extremal parameter$lambda^{ast}>0$ such that for $lambda< lambda^{ast}$, the above problem has a regular solution butfor $lambda> lambda^{ast}$, the probl...

Inthis paper, the main aim is to introduce the class $mathcal{U}_p(lambda,alpha,beta,k_0)$ of $p$-harmonic mappings togetherwith its subclasses $mathcal{U}_p(lambda,alpha,beta,k_0)capmathcal {T}_p$ and $mathcal{U}_p(lambda,alpha,beta,k_0)capmathcal {T}_p^0$, andinvestigate the properties of the mappings in these classes. First,we give a sufficient condition for mappings to be in $mathcal{U}_p(l...