Ketamine has demonstrated usefulness as an analgesic to treat nonresponsive neuropathic pain; however, it is not widely administered to outpatients due to fear of such side effects as hallucinations and other cognitive disturbances. This retrospective chart review is the first research to study the safety and efficacy of prolonged low-dose, continuous intravenous (IV) or subcutaneous ketamine i...

Background: Methylphenidate (MPH) has been used to induce emergence from general anesthesia. OBJECTIVES:  The objective of the present study was to evaluate the effect of MPH on recovery from propofol and ketamine anesthesia in dogs. METHODS: Six healthy male mix-breed dogs weighing 21.9 ± 3.9 kg were used in a randomized crossover design. Thirty minutes after premedication with acepromazine (0...

PURPOSE The aim of this study was to assess the effect of pre- vs postincisional low-dose iv ketamine on postoperative pain in outpatients scheduled for oral surgery under general anesthesia. METHODS Eighty-four patients were randomly assigned to receive intravenously saline before and after surgery in Group 1, ketamine 300 microg x kg(-1) iv before and saline after surgery in Group 2, saline...

Background Shivering is a frequent and undesirable complication of spinal anesthesia. It is a physiologic response to increase the body core temperature in an attempt to raise metabolic heat production. However, shivering may trigger myocardial ischemia; increase intraocular and intracranial pressures, increase wound pain, delay wound healing and interfere with pulse rate, blood pressure and el...

Whether pulse oximeter perfusion index (PI) may be applied to detect the onset of caudal block in pediatric patients under ketamine intravenous basal anesthesia is investigated. 40 ASA I, 2-8-year-old boys scheduled for elective circumcision surgery were randomized into two groups. Group I: 20 patients were anesthetized by 2 mg·kg(-1) ketamine intravenous injection (IV) followed by caudal block...

UNLABELLED The mechanism of tourniquet-induced arterial pressure increase is not known. We investigated the effect of preoperative ketamine on tourniquet-induced arterial pressure and heart rate changes in 85 patients undergoing knee surgery with a tourniquet under general anesthesia. Patients were randomly assigned into three groups; Large Ketamine (n = 28; ketamine 1.0 mg/kg), Small Ketamine ...

BACKGROUND AND AIMS Paediatric cardiac surgery with cardiopulmonary bypass (CPB) is associated with a marked inflammatory response and triggers release of inflammatory cytokines. The aim of this study was to study the effect of ketamine on the inflammatory response during correction of congenital cyanotic heart diseases. METHODS Sixty-six patients with congenital cyanotic heart diseases sched...

An appendectomy operation was undertaken in a 29-year-old patient with signs of an acute crisis of hereditary coproporphyria. Anaesthetic induction with ketamine 75 mg IV was uneventful. The safety of ketamine in patients with coproporphyria is discussed.

introduction: the selective medication for pain control in many clinical situations is morphine but its complications prevent its widespread use. ketamine has been introduced as an alternative for morphine in some studies. however, the efficacy of its solitary use has not yet been evaluated. therefore, the present study was undertaken to evaluate the effect of ketamine alone in relieving pain i...

bronchial asthma represents an increased airways responsiveness to vari¬ous stimulants, leading to reversible obstruction of expiratory flow and chronic inflammatory changes in airways wall. ketamine has been demonstrated to lower airway resistance and to increase lung compliance in the asthmatic patients. in several studies and case reports it has been used successfully in the management of st...