Abstract Objective: The previous studies indicated that the TLRs especially Toll-like receptor 4) TLR4 (are involved in the process of diabetes. The aim of the present research was to investigate the time course expression pattern of TLR4-a main component of innate immune system- in mRNA levels in the heart tissue of diabetic male wistar rats. Materials and Methods: In this research, adu...

Compassion is a complex process that is innate, determined in part by individual traits, and modulated by a myriad of conscious and unconscious factors, immediate context, social structures and expectations, and organizational “culture.” Compassion is an ethical foundation of healthcare and a widely shared value; it is not an optional luxury in the healing process. While the interrelations betw...

conclusions this study suggests that decrease in levels of tlr3 and tlr7 expression is a mechanism that may enable hcv to evade the host innate immune response. results in both groups, we had 13 males and 12 females with a mean age of 48.7 ± 16. tlr3 (6.23 ± 0.91 vs. 3.89 ± 0.85, p < 0.001) and tlr7 (1.48 ± 0.82 vs-1.33 ± 1.18, p < 0.001) expressions were significantly lower in patients with ch...

background macrophages play critical roles in innate immune response in the liver. whether macrophages participate in liver innate immunity against hcv replication is poorly understood objectives the aim of this study was to investigate the role of macrophages in liver innate immunity against hcv replication. conclusions macrophages may play an important role in liver innate immunity against hc...