BACKGROUND Rapid tests are now widely available to assist the diagnosis of influenza; implementation may optimise the use of antiviral and antibiotic agents in the clinical management of influenza. OBJECTIVE To explore the clinical management of children with influenza-like illness (ILI) when rapid influenza tests were and were not performed. METHODS Between 15 January 2007 and 30 April 200...

BACKGROUND In the event of an influenza pandemic, the majority of people infected will be nursed at home. It is therefore important to determine simple methods for limiting the spread of the virus within the home. The purpose of this work was to test a representative range of common household cleaning agents for their effectiveness at killing or reducing the viability of influenza A virus. ME...

Aims: Influenza and the agents responsible for influenza-like illness (ILI) are a significant cause of upper lower respiratory tract infections, with notable pattern seasonal incidence. The surveillance influenza causing ILI is important developmentof prophylaxis approach infection control. In present study, we utilize Reverse transcription-polymerase chain reaction (RT-PCR) method to identify ...

background: the h9n2 subtype of influenza a viruses is considered to be widespread in poultry industry. adamantane is a group of antiviral agents which is effective both in prevention and treatment of influenza a virus infections. these drugs inhibit m2 protein ion channel which has role on viral replication. objectives: the main objective of this study is to evaluate m gene of avian influenza ...

This study conducted at the Research Institute for Tropical Medicine from April 1990 to December 1992, identified the etiology of acute lower respiratory tract infection (ALRI) in 119 (36.9%) of 317 hospitalized children < 5 years of age. A higher proportion of respiratory viruses (27.2%) than bacterial agents (10.7%) were identified. Viral agents (adenovirus, RSV, parainfluenza 3, influenza A ...

The avian influenza (H5N1) viral RNA polymerase protein PA(C) was used as a target to screen nine chlorogenic acid derivatives for their polymerase inhibitor activity. Among them, seven compounds were PA(C) ligands, and four inhibited influenza RNA polymerase activity. These results aid in the design of anti-influenza agents based on caffeoylquinic acid.

Rapid increase in drug-resistant influenza virus isolates, and pandemic threat posed by highly pathogenic avian influenza A and swine flu viruses provide clear and compelling reasons for fast tracking development of novel antiviral drugs. Nucleic acid-based drugs represent a promising class of novel antiviral agents that can be designed to target various seasonal, pandemic and avian influenza v...

The increased concentrations of neutralizing antibodies against influenza A virus in human serum which occur after influenza A do not differentiate between antigenically different strains of this virus or swine influenza virus but instead appear to possess equal reactivity against these agents. The decrease in antibody levels which occurs with time is also independent of the strain of virus use...