human serum paraoxonase (pon) associated with high density lipoprotein (hdl) , has been postulated to have a role in protecting low-density lipoprotein (ldl) against oxidative damage, which has led to the proposal that pon is an anti-atherogenic and anti-inflammatory enzyme. it has genetic polymorphism at the 191 (r ->q) and two alloenzymes a and b and three phenotypes a, b, and ab. we examined...

In this study, genetic diversity of 20 wheat genotypes was evaluated using 126 simple sequence repeats (SSR) alleles, covering all three wheat genomes. A total of 1557 allelic variants were detected for 126 SSR loci. The number of alleles per locus ranged from 4 to 19 and the allelic polymorphism information content (PIC) varied from 0.66 (Xgwm429) to 0.94 (Xgwm212 and Xgw...

Eradication of hepatitis C virus (HCV) infection, both spontaneous and treatment-induced, is marked by the wildtype allele C of a single nucleotide polymorphism upstream of the IL28B gene, rs12979860. This favorable allele was recently described to be in linkage disequilibrium with the wildtype allele TT of a dinucleotide polymorphism, ss469415590, located within a new protein-coding gene. Whil...

conclusions il6 and il8 gene polymorphisms have no role in nash pathogenesis and liver fibrosis process, but presence of the a/a genotype in the il8 gene is associated with disease progression. patients and methods consecutive patients with biopsy proven nash and age- and gender-matched healthy individuals with normal liver function tests and normal ultrasonography were enrolled in the study. h...

the aim of this study was to analyze 22 cytokine polymorphisms in the roma population from the republic of macedonia. the roma population consists of 77 healthy unrelated individuals, residents of different geographical regions of the republic of macedonia (skopje, gostivar, and kochani). blood samples were collected after obtaining written consent. dna was isolated from peripheral blood and 22...

Results We assessed data from 12 patients (gender ratio 1:1), of which 10 had HCV monoinfection and 2 had HCV+HIV coinfection. The mean age was 43.8 ± 16.5 years (range 19-71 years). Eleven patients were infected with HCV genotype 1b, and one patient had been coinfected with genotype 2a/2c but had spontaneously cleared 2a infection and was now monoinfected with HCV 2c. Only one patient had IL28...

background: genetic variation influences susceptibility/resistance to tuberculosis. cxcl10 is involved in t-cell migration and stimulation of natural killer cells in mycobacterium tuberculosis infection. objectives: we aimed to investigate the genetic polymorphisms in promoter of the cxcl10 gene in patients with pulmonary tuberculosis (ptb) and healthy controls, to clarify whether polymorphisms...