BACKGROUND AND PURPOSE Patients with active cancer are at an increased risk for stroke. Hypercoagulability plays an important role in cancer-related stroke. We aimed to test whether 1) hypercoagulability is a predictor of survival, and 2) correction of the hypercoagulable state leads to better survival in patients with stroke and active cancer. METHODS We recruited consecutive patients with a...

e16134 Background: In experimental systems, interference with coagulation can affect tumor biology. We suggested that abnormal coagulation could be a negative predictor for response to immunotherapy and survival among patients with metastatic renal cell carcinoma (MRCC). METHODS To address this issue, retrospective analysis of 289 previously untreated MRCC patients entering on institutional r...

BACKGROUND Subclavian vein thrombosis (SVT) is usually caused by vigorous activity or extensive use of the upper extremity. Patients are tested for hypercoagulability if they present with a spontaneous clot unassociated with such activity. The objective of this study was to determine the prevalence of hypercoagulability in patients undergoing first rib resection and scalenectomy presenting with...

It has been observed that patients with COVID-19 infection may develop acute pulmonary embolism (APE), myocardial infarction, limb thrombosis, and venous / or arterial including central nervous system. Thrombosis formation in can be explained by the virchow triad. Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) directly attack vascular endothelial cells, causing excessive activatio...

Hypercoagulability is a state in which the hemostatic balance shifts toward excessive platelet activation and fibrin deposition, leading to thrombosis. Although a definitive diagnosis is often difficult to make, identifying patients at risk for thromboembolism is critical. By identifying these patients and understanding mechanisms that contribute to hypercoagulability, clinicians can select pro...

It has been suggested that dipyrimadole might be effective in reducing the incidence of thrombosis by interfering with both platelet clumping and the early stages of blood clotting. Emmons et al (1965 a & b) found that dipyrimadole inhibited thrombus formation in injured rabbit vessels in vivo, and reduced platelet stickiness in vitro, and they suggested that dipyrimadole might be a useful agen...