background: diabetes mellitus type 2 with dyslipidemia is a common disease. previous studies suggest that chemical constituent present in pinus eldarica (p. eldarica) nut posesess antioxidant properties and positively affect glucose metabolism. however blood glucose and cholesterol lowering effects of p. eldarica nut have not been studied so far. objective: the present study was undertaken to e...

OBJECTIVE We aimed to illustrate the histogenesis, lactic dehydrogenase isoenzymes electrophoresis, and DNA damage of cardiac muscles and blood vessels during prenatal life of maternal diabetic or hypercholesterolemic mother. METHODS Eighty fertile male and virgin female Wistar rats (1 male/3 females), weighing approximately 130 g, were mated and zero date of gestation was determined. Diabete...

Background: Diabetes mellitus type 2 with dyslipidemia is a common disease. Previous studies suggest that chemical constituent present in pinus eldarica (P. eldarica) nut posesess antioxidant properties and positively affect glucose metabolism. However blood glucose and cholesterol lowering effects of P. eldarica nut have not been studied so far. Objective: The present study was undertaken to...

The leaves or seeds powder of fenugreek (Trigonella foenum-graecum) were orally administered in the diet to hypercholesterolemic male rats for 8 weeks to test their effect on lipid profile, antioxidants enzymes and lipid peroxide. Twenty four male rats weighing 150-170 gm were divided into four groups. The first group is untreated (control group), fed basal diet, the second group, fed on 2% cho...

Dyslipidemia is related to the progression of atherosclerosis and is an important risk factor for acute coronary syndromes. Our objective was to determine the effect of rosuvastatin on myocardial necrosis in an experimental model of acute myocardial infarction (AMI). Male Wistar rats (8-10 weeks old, 250-350 g) were subjected to definitive occlusion of the left anterior descending coronary arte...

Introduction: Spices are now considered as agents that not only can prevent but may even treat chronic diseases. This study was aimed to investigate the effects of Allium hirtifolium as a hypolipidemic and anti-atherosclerotic substance in hypercholesterolemic rabbits. Methods: Twenty four adult New Zealand male rabbits were divided randomly into 3 groups of 8 animals each and treated for 60 da...

INTRODUCTION Metabolic acidosis is present in end stage renal disease. There is a link between enhanced endothelial permeability and accelerated atherosclerosis. In this study, we investigated the effect of experimentally induced metabolic acidosis on aortic endothelial permeability and serum nitric oxide (NO) concentration in normal and high-cholesterol fed rabbits. MATERIAL AND METHODS Twen...

results administration of dse significantly increased serum paraoxonase and arylesterase activities in treated hypercholesterolemic groups compared to untreated ones. there was a significant difference in the taoc of serum between the normal diet and hypercholesterolemic groups. however, dse did not change the taoc in hypercholesterolemic groups significantly. conclusions dse increases serum pa...

The aim of this study was to assess how cerivastatin influences contractility and degree of myocardial damage in papillary muscle subjected to hypoxia-reoxygenation in hypercholesterolemic guinea pigs. Study group consisted of guinea pigs, fed standard, hypercholesterolemic or hypercholesterolemic diets with low dose of cerivastatin. During experimental hypoxia-reoxygenation, the contractility ...