UNLABELLED Myxoedema madness was first described as a consequence of severe hypothyroidism in 1949. Most cases were secondary to long-standing untreated primary hypothyroidism. We present the first reported case of iatrogenic myxoedema madness following radioactive iodine ablation for Graves' disease, with a second concurrent diagnosis of primary hyperaldosteronism. A 29-year-old woman presente...

Aldosterone, the major circulating mineralocorticoid, participates in blood volume and serum potassium homeostasis. Primary aldosteronism is a disorder characterised by hypertension and hypokalaemia due to autonomous aldosterone secretion from the adrenocortical zona glomerulosa. Improved screening techniques, particularly application of the plasma aldosterone:plasma renin activity ratio, have ...

54-year-old male patient was admitted in endocrine ward and referred to our hospital for psychiatric consult due to malaise symptoms , dysphoric mood, irritability, insomnia, loss of appetite, increasing the amount of speech, lack of enjoyment of life, hopelessness, thoughts of worthlessness ,thoughts of death (these symptoms was started from 4 months ago ,after some career change ). other symp...

Cirrhotic ascites, in which secondary hyperaldosteronism is a notable feature, is associated with impaired gastric secretion (Baddeley, 1968). Obstruction to hepatic venous outflow, which also induces secondary hyperaldosteronism and ascites (Orloff, Ross, Baddeley, Nutting, Spitz, Sloop, Neesby, and Halasz, 1964), depresses acid secretion from Heidenhain pouches in dogs with cirrhotic and non-...

The common practice of encouraging forearm exercise as an aid to venepuncture is a potent source of erroneously high plasma potassium levels. This may be sufficient to obscure a suspicion of hyperaldosteronism, with possible serious repercussions in hypertensive patients, in whom the diagnosis of hyperaldosteronism has important therapeutic implications. Plasma is preferable to serum for potass...