Background and Aims: Sexually transmitted infections (STIs) are of major concern to clinicians and researchers in the field of reproductive medicine. Many STI pathogens cause incurable and often fatal diseases, and have been transmitted through insemination procedures. The role of herpes simplex virus in male infertility has been investigated using the sensitive methods. The aim of this study w...

Avicennia marina (Avicenniaceae) is a species of mangrove tree used for treatment of small pox lesions in Persian folk medicine. The antiviral activity of methanol, ethanol, water, chloroform and n-hexane extracts was evaluated against HIV-1 and HSV. Methanol extract had the highest antiviral activity and the most polar fraction of this extract (fraction D) inhibited HSV with TI and SI values o...

herpes simplex virus type 1 (hsv-1) is a member of the herpesviridae family that causes herpetic disease in human. during the last 25-30 years, many investigations have been conducted on pathogenesis and molecular biology of this virus in several countries. in iran hsv-1 has been isolated from patients and detected using immunological techniques. in this study, we investigated the molecular asp...

Background: Herpes simplex virus type 2 (HSV-2) seroprevalence has been shown to be a potential sign of infection in pregnant women, and it could be applied to check HSV-2 transmission. This study evaluated the anti-HSV-2 IgG prevalence in pregnant women who were referred to health centers in Urmia, Northwest of Iran, during 2014-2015. Methods: Serum samples were collected from 86 pregnant wome...

Background: Breast cancer develops due to the combination of external and internal risk factors. Also, role viruses is considerable in developing breast cancer. Objectives: This study compared frequency herpes simplex virus types 1 2 (HSV-1 HSV-2) level IgM IgG antibodies against HSV between patients healthy individuals. Methods: Sixty women with 60 (40 fibroadenoma 20 good health) were selecte...

Abstract Background The role of viruses as a cause breast cancer (BC) has been significantly investigated in recent years. Human papillomavirus (HPV) detected invasive carcinomas, while most studies have only focused on the detection viral DNA, we aimed to examine prevalence and genotypes HPV among Iranian BC patients. We also examined presence herpes simplex-1 (HSV-1), simplex-2 (HSV-2), varic...

Background: Herpes simplex virus type 1 (HSV-1) causes serious illness in humans, especially newborns and immunocompromised hosts. Public health requires the development of new, less toxic anti-HSV-1 drugs. Objectives: This study aimed to evaluate potential anti-herpesvirus activity natural products an extensive library 133 compounds by examining viral titers number plaques. Methods: (S)-10-hyd...