Shorea robusta Gaertn. f. (Sal) is one of the most important traditional Indian medicinal plants. The resin of the plant has been used in the treatment of inflammation in folklore medicine. In the present study, ethanolic extract (70%) of S. robusta resin (SRE) was investigated for its anti-inflammatory and antipyretic activities. Acute inflammation was produced by carrageenan-induced hind paw ...

INTRODUCTION Grangea maderaspatana (L.) Poir. (Asteraceae), a popular Indian medicinal plant is traditionally used for rheumatism in the knee joint and pain in the muscles. AIM To investigate antinociceptive and antirheumatic activity of G. maderaspatana (L.) Poir. using experimental models. MATERIALS AND METHODS Antinociceptive activity of methanolic extract of G. maderaspatana (L.) Poir. ...

Water immersion is widely used in physiotherapy and might relieve pain, probably by activating several distinct somatosensory modalities, including tactile, pressure, and thermal sensations. However, the endogenous mechanisms behind this effect remain poorly understood. This study examined whether warm water immersion therapy (WWIT) produces an antiallodynic effect in a model of localized infla...

The ethyl acetate, chloroform extracts, and the two ‰avonoids kaempferol 1 and kaempferol-3-O-glucoside 2 isolated from whole plants of Thesium chinense Turcz were investigated for their antiin‰ammatory and analgesic activities. For the antiin‰ammatory activity, carrageenan-induced hind paw edema and xylene-induced mouse ear edema models, and for the analgesic activity, the acetic acid-induced ...

Piper interruptum Opiz. and Piper chaba Linn. are herbaceous plants in the Piperaceae family. The ethanol extract of P. interruptum and P. chaba inhibited ethyl phenylpropiolate-induced ear edema and carrageenan-induced hind paw edema in rats. Both extracts reduced transudative and granuloma weights as well as body weight gain and thymus weight of the chronic inflammatory model using cotton pel...

OBJECTIVES The purpose of the present study was to investigate the anti-inflammatory properties of aqueous extract of the leaves of H. integrifolia, Planch. MATERIALS AND METHODS The hind paw edema was produced in rats by subplanter injection of carageenan. The aqueous extract of H. integrifolia, Planch. (AHI) at dose (250 and 500 mg/kg p.o) was given to observe % inhibition of paw edema whic...

The potential effects of flavonoids, phenylethanoid and neolignan glycosides from the aerial parts of Verbascum salviifolium Boiss. were studied in the p-benzoquinone-induced writhing reflex, for the assessment of the antinociceptive activity, and in carrageenan- and PGE1-induced hind paw edema and 12-O-tetradecanoyl-13-acetate (TPA)-induced ear edema models in mice, for the assessment of the a...

objective: crocin, as an active constituent of saffron, has many biological functions including antioxidant and anti-inflammatory activities. the present study was aimed to investigate the effects of crocin and chlorpheniramine on local edema induced by histamine. materials and methods: local edema was induced by subcutaneous injection of histamine (100 μl, 0.1%) in ventral surface of right hin...

Objective: Crocin, as an active constituent of saffron, has many biological functions including antioxidant and anti-inflammatory activities. The present study was aimed to investigate the effects of crocin and chlorpheniramine on local edema induced by histamine. Materials and Methods: Local edema was induced by subcutaneous injection of histamine (100 μl, 0.1%) in ventral surface of right hi...

In the present study, the analgesic and anti-inflammatory activity of 95% ethanolic extract of Woodfordia fruticosa (WFE) flowers in acute, subacute and chronic models of inflammation was assessed in rats and mice. Oral administration of WFE (250 and 500 mg/kg) exhibited significant anti-inflammatory activity in acute (carrageenin and autocoids induced hind paw edema), subcute (formaldehyde-ind...