BACKGROUND A typical growth pattern with decreased pubertal growth spurt has been identified in patients with classical congenital adrenal hyperplasia (CAH). OBJECTIVE To evaluate the accuracy of final height predictions in patients with CAH using the Bayley and Pinneau (B&P) method. PATIENTS AND METHODS Using growth and final height data of 92 patients (57 F/35 M) with CAH due to 21-hydrox...

PURPOSE To estimate the height loss in 28 patients who had undergone surgery for scoliosis before skeletal maturity. METHODS 28 women patients aged 11 to 18 (mean, 15) years underwent Harrington instrumentation, segmental sublaminar wiring, and posterior spinal fusion for idiopathic scoliosis. The patients' mean age at menarche was 13 (range, 10-16) years. Pre- and post-operative radiographs ...

BACKGROUND It has been suggested that longitudinal rather than cross-sectional growth standards be used to assess individual growth patterns. Thus, the aim of this study was to follow boys and girls throughout their pubertal years, so that a mixed longitudinal growth curve of height, weight, sitting height, arm span, skinfold thickness, body mass index (BMI), and the ratio of sitting height or ...

INTRODUCTION The most frequent physical features associated with Turner syndrome is short stature. The main goal of the research was to estimate the height of women with Turner syndrome and to analyze the correlation between their height and their sisters and parents height. MATERIAL AND METHODS The research was based on the 176 women with Turner syndrome (number of parents = 176; number of s...

http://www.sciencemag.org/cgi/content/full/308/5729/1801 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/1106215/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://www.s...

QUESTION UNDER STUDY We determine the causes of secular changes in the average height of the male Swiss population for the first time by analysing an unbiased, individually measured, highly representative height-data sample of 18- and 19-year-old Swiss conscripts (N = 458,322) at the national level spanning the years 1992 to 2009. Furthermore, we add historical context based on earlier data fro...

Socio-economic inequalities in attained height have been reported in many countries. The aim of this study was to explore the age at which maternal education inequalities in child height emerge among children from a middle-income country. Using data from the 2004 Pelotas cohort study from Brazil we modelled individual height growth trajectories in 2106 boys and 1947 girls from birth to 4 years ...

CONTEXT Patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency typically reach a final adult height well below their mid-parental target height. OBJECTIVE The objective of this study was to examine whether GH alone or in combination with an LHRH analog (LHRHa) improved the final adult height in patients with CAH. DESIGN The study was a nonrandomized prospective ...

Adult height is associated with testicular cancer risk. We studied to what extent this association is explained by parental height, childhood height and age at puberty. We conducted a case-control study on germ-cell testicular cancer patients diagnosed in 1997-2008 and resident in the Province of Turin. Information was collected using mailed questionnaires in 2008-2011. Specifically, we asked f...

INTRODUCTION Short-term studies have shown that inhaled corticosteroids may retard the growth of children with asthma. The effect of long-term treatment on adult height is, however, uncertain. MATERIAL AND METHODS We conducted a prospective study of children with asthma to examine the effect of long-term treatment with inhaled budesonide on adult height. We report on 211 children who have att...