نتایج جستجو برای: guanidinoacetic acid

تعداد نتایج: 747445  

Journal: :The British journal of nutrition 2013
Sergej M Ostojic Barbara Niess Marko Stojanovic Milos Obrenovic

Guanidinoacetic acid (GAA) is the natural biosynthetic precursor of creatine, in a metabolic reaction that requires only a methyl group transfer. The use of GAA as a food additive for restoring creatine load in human tissues is rather unexplored and data on efficacy and safety are limited. In particular, an increase in serum homocysteine after GAA administration can be regarded as critical and ...

Journal: :Revista Brasileira De Zootecnia 2023

In this study, we evaluated how guanidinoacetic acid (GAA) addition in diets with various metabolizable energy (ME) contents affects the performance of broiler chickens. We also estimated equivalence GAA ME. distributed 1,280 one-day-old broilers a completely randomized design eight treatments, replicates, and twenty birds per experimental unit. Treatments were based on ME levels (2,775-2,875-2...

2014
ASHLEY DEGROOT Ryan N. Dilger Carl M. Parsons Hans H. Stein Matt Nothnagel Ryan Dilger Carl Parsons Hans Stein

Guanidinoacetic acid is formed from Arg and is the immediate precursor to creatine (Cre). A study was conducted to determine the ability for GAA to spare Arg in broiler chicks fed an Arg-deficient practical diet. A common basal diet (0.84% digestible Arg) was supplemented with combinations of Arg (0 or 0.16%) and GAA (0, 0.06, or 0.12%) to form a 2 × 3 factorial arrangement of dietary treatment...

Journal: :Clinical chemistry 1987
Y Shirokane M Utsushikawa M Nakajima

We developed and evaluated a colorimetric method for enzymic determination of guanidinoacetic acid (GAA) in urine. Endogenous urinary urea was first eliminated by urease (EC 3.5.1.5), and the added urease was then removed from the sample by centrifugal ultrafiltration. GAA in the ultrafiltrate was subsequently hydrolyzed by guanidinoacetate amidinohydrolase (EC 3.5.3.2) to glycine and urea. The...

Journal: :Clinical chemistry 1991
Y Shirokane M Nakajima K Mizusawa

(urinary creatinine concentration). Because most of the serum results referred to were below or close to the detection limits of the kits, the urine results would be expected to he negative with the qualitative tests. The NovoClone HCG kit measures intact HCG as well as free 13-chains. The Delfia kit from Pharmacia measures the intact HCG molecule only. This difference might explain the only re...

Journal: :Blood purification 2010
Eva Schepers Griet Glorieux Laetitia Dou Claire Cerini Nathalie Gayrard Loïc Louvet Charlotte Maugard Pierre Preus Maria Rodriguez-Ortiz Angel Argiles Philippe Brunet Gerald Cohen Joachim Jankowski Vera Jankowski Ziad Massy Mariano Rodriguez Raymond Vanholder

Chronic kidney disease is considered a major cause of cardiovascular risk and non-traditional risk factors remain largely unknown. The in vitro toxicity of 10 guanidino compounds (GCs) was evaluated via a standardized approach on different cell systems of relevance in cardiovascular disease. The parameters evaluated were production of reactive oxygen species, expression of surface molecules, ce...

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