This paper discusses recent work by the authors which has investigated the nutritional regulation of glycogen concentration in skeletal muscle of sheep and cattle. Several experiments are summarised which show a clear relationship between the level of glycogen in muscle and the intake of metabolisable energy. This translates into strong seasonal effects on muscle glycogen in pasture fed cattle....

McArdle disease (muscle glycogenosis type V) is a disease caused by myophosphorylase deficiency leading to "blocked" glycogen breakdown. A significant but varying glycogen accumulation in especially distal hind limb muscles of mice affected by McArdle disease has recently been demonstrated. In this study, we investigated how myophosphorylase deficiency affects glucose metabolism in hind limb mu...

To investigate the regulatory effect of d-alloxan on glucose metabolism and lipid in diabetic mice. Twenty five mice were divided into control group, fructose group cellulose group. The results showed that blood each reached peak at 90 min concentration was significantly lower than other groups (p<0.05). higher before after meal (p<0.05), liver glycogen insulin level groups, but difference not ...

Insulin-stimulated glucose uptake and incorporation of glucose into skeletal muscle glycogen contribute to physiological regulation of blood glucose concentration. In the present study, glucose handling and insulin signaling in isolated rat muscles with low glycogen (LG, 24-h fasting) and high glycogen (HG, refed for 24 h) content were compared with muscles with normal glycogen (NG, rats kept o...

In this study, we analyzed the influence of phosphate (P(i)) limitation on the metabolism of Corynebacterium glutamicum. Metabolite analysis by gas chromatography-time-of-flight (GC-TOF) mass spectrometry of cells cultivated in glucose minimal medium revealed a greatly increased maltose level under P(i) limitation. As maltose formation could be linked to glycogen metabolism, the cellular glycog...

Chronic ethanol consumption has been shown to significantly decrease hepatic glycogen content; however, the mechanisms responsible for this adverse metabolic effect are unknown. In this study, we examined the impact chronic ethanol consumption has on time-of-day-dependent oscillations (rhythms) in glycogen metabolism processes in the liver. For this, male C57BL/6J mice were fed either a control...

The milkfish, Chanos chanos , is an important aquaculture species that can be cultured in freshwater (FW) and seawater (SW) ponds because of its high euryhalinity. In winter, cold snap leading to mortality this tropical a critical issue for the industry Taiwan. Under hypothermal stress, however, changes energy supply osmoregulation euryhaline intriguing. study, we used antibody against glycogen...

It is well known that an increase in glycogen content is one of the metabolic changes which estrogen induces in rat uterus, the target organ of the hormone . Although glycogen in the uterus has been considered to be an energy and nutritional source for the implan tation and growth of fertilized ovum, the mechanism of glycogen synthesis in the uterus and the biological significance of the elevat...

Fenfluramine, an anorexigenic agent, is widely used in the treatment of obesity. Besides its anorectic effect, it may also have some effects on general metabolism with the consequence of weight loss. In this study, the effect of fenfluramine on the concentrations of some parameters related to carbohydrate metabolism was investigated. It was shown that the serum insulin level was reduced by ...