This study aims to detect the mRNA of p53β and Δ133p53 isoforms in three gastric carcinoma cell lines and tissues of superficial gastritis, atrophic gastritis, gastric carcinoma, or paracancerous area. Nested reverse transcription PCR was used to detect the mRNA of p53β and Δ133p53 isoforms in tissues of superficial gastritis, chronic atrophic gastritis, gastric cancer cell lines (SGC-7901, MKN...

Nodular gastritis is a Helicobacter pylori-related gastritis with endoscopically proven gooseflesh skin-like nodularity in the gastric antrum. Although an association between nodular gastritis and gastric malignancies has been suggested, there is neither a treatment strategy nor a treatment guideline for this condition because of its relative rarity. We have recently experienced two cases of di...

Gastric adenocarcinoma occurs via a sequence of molecular events known as the Correa's Cascade which often progresses over many years. Gastritis, typically caused by infection with the bacterium H. pylori, is the first step of the cascade that results in gastric cancer; however, not all cases of gastritis progress along this carcinogenic route. Despite recent antibiotic intervention of H. pylor...

Although the aetiology and pathological significance of chronic atrophic gastritis is still unknown, the incidence of the disorder in normal subjects and in a variety of pathological conditions is becoming known. Coghill (1960), in a full review of the subject, discussed the possible relationship between gastritis and hypochromic anaemia. It has been suggested that the gastric mucosal lesion ma...

The aim of the study was to ascertain the existence of intestinal metaplasia in gastric mucosa of patients with gastric carcinoma coupled with H. pylori positive chronic atrophic gastritis and possible connection of IM with the development of gastric carcinoma. The paper presents prospective study that included 50 patients with gastric carcinoma and 50 patients with chronic atrophic H. pylori p...

Gastritis cystica polyposis (GCP) is a rare benign hyperplastic polypoid neoplasm that usually occurs on the gastric side of anastomoses in patients who have previously undergone gastroenterostomy surgery. Only few cases GCP been reported unoperated stomach. Here we present 73-year-old female investigation for altered bowel habits was found to polyp diagnosed as GCP. Both endoscopic and radiolo...

INTRODUCTION Diseases of upper gastrointestinal tract are responsible for a great deal of morbidity and mortality. The histopathological study of endoscopic biopsies permits exact diagnosis for further management.The aim of this study is to find out the histopathological pattern of endoscopic biopsy. METHODS A descriptive study was conducted in consecutive endoscopic gastric biopsies in a Hosp...

BACKGROUND Nodularity on the gastric mucosa is occasionally seen in general practice. There is no consensus about the association of nodular gastritis and histological premalignant lesions. This study is designed to investigate the prevalence of histological premalignant lesions in dyspeptic patients with endoscopic nodular gastritis. METHODS Consecutive patients with endoscopic nodular gastr...

Gastritis cystic polyposa/profunda (GCP) is defined as a hyperplastic polyp that contains foci of misplaced foveolar and/or glandular epithelium in the muscularis mucosae or in the deeper portions of the submucosa or the muscularis propria [1-6]. The lesion called polyposa when an intraluminal polyp is present [1,2] and profunda when the cystic lesion located within the submucosa [3] and the bu...

Acute haemorrhagic gastritis is one of the most frequent causes of severe upper gastrointestinal haemorrhage. In series in which a positive diagnosis is made by endoscopy or laparotomy the incidence is approximately 25 %1,2,3. It is frequently related to recent aspirin ingestion5 and is also seen after major surgery or trauma ('stress' ulcers),6 but may occasionally appear in the absence of any...