Gastric pH and volume were measured in 87 patients who had received i.v. omeprazole (a new gastric antisecretory agent) 40 mg or placebo 1 or 3 h before surgery. Omeprazole increased the pH of gastric contents in the majority of patients. Administration 1 h before surgery produced greater gastric pH and smaller volume than administration 3 h before surgery. There was a reduction in the number o...

BACKGROUND Chronic kidney disease (CKD) is a highly prevalent condition in cats. Advanced CKD is associated with hyporexia and vomiting, which typically are attributed to uremic toxins and gastric hyperacidity. However, gastric pH studies have not been performed in cats with CKD. HYPOTHESIS/OBJECTIVES To determine if cats with CKD have decreased gastric pH compared to age-matched, healthy cat...

Luminal amino acids and lack of luminal acidity as a result of acid neutralization by intragastric foodstuffs are powerful signals for acid secretion. Although the hormonal and neural pathways underlying this regulatory mechanism are well understood, the nature of the gastric luminal pH sensor has been enigmatic. In clinical studies, high pH, tryptic peptides, and luminal divalent metals (Ca(2+...

Gastric secretion of hydrochloric acid requires protons and chloride, yet the mechanisms and regulation of gastric chloride secretion remain unclear. We developed an in vivo technique to simultaneously measure acid/base and chloride secretion into the gastric lumen of anesthetized rats. The cannulated stomach lumen was perfused with weakly pH-buffered chloride-free solution containing a chlorid...

The effects of magnesium trisilicate mixture B.P.C., sodium citrate mixture or cimetidine on gastric pH and aspirated gastric volumes were compared in 78 obstetric patients during elective (a), or emergency (b) surgery. Magnesium trisilicate mixture B.P.C. was associated with the most alkaline values of gastric pH (mean (a) 7.9, (b) 7.3; range 2.9-9.1). Sodium citrate 0.3 mol litre-1 mixture re...

PURPOSE To assess gastric pH and its relationship with urease-test positivity and histological findings in children with Helicobacter pylori infection. METHODS Fasting gastric juices and endoscopic antral biopsy specimens were collected from 562 children and subjected to the urease test and histopathological examination. The subjects were divided into 3 age groups: 0-4, 5-9, and 10-15 years. ...

Samples of gastric juice were collected from 60 fasting subjects ranging from 10 to 80 years of age. Seventy-six per cent of the gastric cultures were positive. Natural gastric flora were classified into those organisms found frequently and sporadically. Effect of gastric pH on bacterial growth has indicated an increase in the number of samples showing growth above pH 5. Yeast was the only orga...

The development of in vitro digestion models relies on the availability of in vivo data such as digestive enzyme levels and pH values recorded in the course of meal digestion. The variations of these parameters along the GI tract are important for designing dynamic digestion models but also static models for which the choice of representative conditions of the gastric and intestinal conditions ...

Changes in gastric pH of leopard sharks Triakis semifasciata were quantified as an indicator of feeding frequency and ration size. Continuous in situ measurements of gastric pH were made in captive adult leopard sharks using an autonomous pH/temperature probe for periods ranging from 5-16 days. Instrumented sharks were fed meals of squid at different ration sizes. Gastric fluid samples were als...

The highest extractable concentration in the artificial sweat fluid was observed for Ba (120mg/kg; d.w.). The highest extractable concentration in the artificial gastric fluid was observed for Al (9030mg/kg; d.w.). Furthermore, the extractable concentrations of Ba (550mg/kg; d.w.) and Zn (400mg/kg: d.w.) in the bottom ash using artificial gastric fluid were elevated. The extractable concentrati...