The histopathology of bone is described in 60 patients with chronic renal failure due to a variety of renal diseases. Changes of azotaemic renal osteodystrophy included osteitis fibrosa, osteomalacia, and osteosclerosis. Quantitative histology using a point-counting technique revealed a significant increase in total bone, mineralized bone, and osteoid in comparison with a control group of 68 in...

Bronchiolitis fibrosa obliterans, described first by Lange in 1901, is an obliterative process of the bronchioles in which there is extensive damage to the bronchial wall involving all the constituent elements (the epithelium, elastic tissue, and muscle fibres), and the lumen is partially or totally occluded by bronchial exudate organized by fibroblasts and capillaries. The disease is extremely...