Our goal is to prove that during corneal perforation, when it larger than 3 mm, we should not rush perform keratoplasty (cornea transplant). First, do our best and fight the end preserve a patient's own cornea, in which amniotic membrane will help us. In 15 patients with where size of perforation exceeded 3-4 surgical treatment was performed piece applied cornea. 14 out 15, their cornea moderat...

METHODS. Corneal epithelial debridement wounds of two sizes (1.5 and 2.5 mm) were made on the ocular surface of BALB/c mice and were evaluated at various times after wounding. Corneas were processed either as whole mounts and stained with propidium iodide and an antibody against 9 integrin or for bromodeoxyuridine analyses of cell proliferation. A separate study involved analyses of corneal wou...

background: the ostrich is an interesting subject concerninganimal evolution and morphology studies. it has been speculatedthat ostrich eyes would have distinct tissue structures and this hasnot been previously studied in detail. objectives: the aim of thepresent study was to investigate the histology of the outer layer ofthe ostrich. methods: ten mature ostriches were chosen from anostrich bre...

background: the aim of the present study was to evaluate the efficacy of autologous serum eye drop in treatment of recurrent corneal epithelial defect. m aterials and methods: fourteen patients with recurrent corneal epithelial defect were studied. autologous serum was prepared from the patients and diluted in 20% normal saline. the patients were instructed to use the autologous serum every six...

extractdefective corneas are the leading cause of blindness world wide and the second leading cause, after diabetic retinopathy,of blindness in the united state , afflicting 30000 americans each year. happily, nearly 95 percent of those who have corneal transplantations( in 1985 they numbered,26300) regain their sight. the cornea is a transparent, a vascular, dim-sized tissue continious with th...

We describe herein a case of an impending corneal perforation with a large descemetocele in a patient with previous penetrating keratoplasty (PKP) that subsequently was treated with an emergent lamellar keratoplasty using frozen preserved cornea. A 76-year-old male patient, who had a PKP, presented with a completely whitish and edematous graft accompanied by large epithelial defects. Although a...

PURPOSE To study the natural movement of corneal epithelial cells in the normal adult mouse with histology and in vivo microscopy. METHODS A transgenic mouse line that was engineered to ubiquitously express green fluorescent protein (GFP) was used to visualize corneal epithelial cells. For histology, epithelial GFP was imaged in a wholemounted cornea en face, and also in frozen cross-sections...

PURPOSE The purpose of this study was to examine expression of platelet-derived growth factor (PDGF) and PDGF receptors in the human cornea and to study the effects of the PDGF isotypes on proliferation and chemotaxis of human corneal fibroblasts. The effects of interleukin (IL)-1alpha, bone morphogenic protein (BMP)2, and BMP4 on chemotaxis of human corneal fibroblasts were also studied. MET...