نتایج جستجو برای: frailty models
تعداد نتایج: 915874 فیلتر نتایج به سال:
In recent years, it has been shown that individual heterogeneity in the acquisition of infectious diseases has a large impact on the estimation of important epidemiological parameters such as the (basic) reproduction number. Therefore, frailty modeling has become increasingly popular in infectious disease epidemiology. However, so far, using frailty models, it was assumed infections confer life...
Background: Breast cancer is one of the most common recurrence cancers among women. There are several factors that can affect the multiple recurrence of this disease, which have been studied and recognized in various studies, however, with the fact that these factors are known, can not always accurately predict the incidence of metastasis. On the other hand, simultaneous examination of the type...
This talk gives an overview about the analysis of twin data on diseases, aging and longevity. One goal of our research in this area is the evaluation of the genetic contribution to life span and mortality from different causes. Such evaluation is performed using the idea of correlated frailty. We apply different correlated frailty models to the analysis of bivariate survival data from Danish, F...
We present the frailtyHL package for fitting semi-parametric frailty models using hlikelihood. This package allows lognormal or gamma frailties for random-effect distribution, and it fits shared or multilevel frailty models for correlated survival data. Functions are provided to format and summarize the frailtyHL results. The estimates of fixed effects and frailty parameters and their standard ...
Frailty, a critical intermediate status of the aging process that is at increased risk for negative health-related events, includes physical, cognitive, and psychosocial domains or phenotypes. Cognitive frailty is a condition recently defined by operationalized criteria describing coexisting physical frailty and mild cognitive impairment (MCI), with two proposed subtypes: potentially reversible...
Hidden differences in the survival chances of individuals in a population influence the shape of the mortality rate observed in demographic and epidemiological studies. To evaluate the contribution of such hidden variations to observed hazards, frailty models have been suggested. The application of these models to the analysis of survival data in demography, epidemiology, and biostatistics has ...
BACKGROUND The gamma-Gompertz model is a fixed frailty model in which baseline mortality increases exponentially with age, frailty has a proportional effect on mortality, and frailty at birth follows a gamma distribution. Mortality selects against the more frail, so the marginal mortality rate decelerates, eventually reaching an asymptote. The gammaGompertz is one of a wider class of frailty mo...
Description streg performs maximum likelihood estimation for parametric regression survival-time models. streg can be used with singleor multiple-record or singleor multiple-failure st data. Survival models currently supported are exponential, Weibull, Gompertz, lognormal, loglogistic, and generalized gamma. Parametric frailty models and shared-frailty models are also fit using streg. Also see ...
By existing censor and skewness in survival data, some models such as weibull are used to analyzing survival data. In addition, parametric and semiparametric models can be obtained from baseline hazard function of Cox model to fit to survival data. However these models are popular because of their simple usage but do not consider unknown risk factors, that's why cannot introduce the be...
BACKGROUND Frail elderly people experience elevated mortality. However, no consensus exists on the definition of frailty, and many frailty scores have been developed. The main aim of this study was to compare the association between 35 frailty scores and incident cardiovascular disease (CVD), incident cancer, and all-cause mortality. Also, we aimed to assess whether frailty scores added predict...
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