Torrado Pacheco et al. demonstrate that downward firing rate homeostasis occurs when cellular activity levels increase beyond baseline, but only during sleep-dense periods. In contrast, Hebbian-facilitated changes in occur independently of sleep and wake states.

Spike sequence is generated from an underlying firing rate „ Spike sequence (activity of a single neuron) time 1 t 2 t 3 t 6 t … 7 t 8 t BACKGROUND Firing rate function Firing rate conveys information Estimation of firing rate from spike sequence | Firing rate estimation from a single sequence

Many experimental studies concerning the neuronal code are based on graded responses of neurons, given by the emitted number of spikes measured in a certain time window. Correspondingly, a large body of neural network theory deals with analogue neuron models and discusses their potential use for computation or function approximation. All physical signals, however, are of limited precision, and ...

How are firing rates in a spiking network related to neural input, connectivity and network function? This is an important problem because firing rates are a key measure of network activity, in both the study of neural computation and neural network dynamics. However, it is a difficult problem, because the spiking mechanism of individual neurons is highly non-linear, and these individual neuron...