Objective: To determine the frequencies of various benign breast diseases (BBD) in female patients in three private hospitals of Hyderabad. Methodology: This is a prospective cohort study of all female patients visiting the surgical clinic with breast problems. This study was conducted at Isra University Hospital Hyderabad and two other private hospitals of Hyderabad over a period of about thre...

Key words: 1,25-dihydroxicholecalciferol; fibrocystic There was no family history of hypophosphataemia. Physical examination revealed severe proximal-muscle disease of breast; hyperphosphaturia; hypophosphatae-mia; oncogenous osteomalacia weakness. A firm, movable mass, measuring 3 cm in diameter was identified in the soft tissue of the left breast. The results of complete blood cell count, bio...

Our analysis of 1051 breast biopsies in West Indian women under the age of 30 y revealed that 99% of the breast lumps were benign. Fibroadenoma was the commonest (67%) lesion and there was a steady increase in the frequency of fibrocystic disease with age. Carcinoma in this group is therefore rare. Thus most patients can be reassured with certainty of their benign disease and have biopsy at a c...

OBJECTIVE The aim of this study was to examine the expression of matriptase and survivin in breast carcinoma and correlate with clinicopathological parameters. METHODS Immunohistochemical analysis of matriptase and survivin were performed in tissue microarray slides of 290 cases, including 11 normal breast tissue; 27 fibrocystic disease; 17 fibroadenoma; 6 atypical ductal hyperplasia; 39 duct...

The identification of genetically susceptible individuals may permit the determination of genetic and environmental interactions which result in disease. This paper presents some recent findings on possible genetic-environmental interactions in breast disease as determined by a "nature-nurture" model employing epidemiological risk factors and cytologic studies of breast secretions obtained by n...