نتایج جستجو برای: fibroblasts

تعداد نتایج: 62360  

Ali Reza Rafati, Davood Mehrabani, Mahdokht Mahmoodi, Seyedeh-Sara Hashemi,

BACKGROUND Wound healing is a complex and dynamic process following damage in tissue structures. Due to extensive skin damage caused by burn injuries, this study determined the role of human adult peripheral and umbilical cord blood platelet-rich plasma on proliferation and migration in human skin fibroblasts. METHODS Platelet-rich plasma (5, 10, 15, 20 and 50% PRP) from human umbilica...

ژورنال: Anatomical Sciences Journal 2012
Bayat , Mohammad , Esmaeelinejad, Mohammad, Dadpay , Masoumeh,

Purpose: Low level laser therapy is suggested as a new therapeutic method in diabetic wound healing. This survey aimed to evaluate the effects of low level laser on human fibroblasts cultured in high glucose cultures. Materials and Methods: The human skin fibroblasts were cultured under standard condition. The cells were cultured in high glucose culture medium (15mM/L) for a week and two weeks ...

Journal: :medical journal of islamic republic of iran 0
ame nouri from the department of immunology and experimental dermatology, the london hopital, london ei 2a d im leigh j mangera a shamsa the 'mashhad university of medical sciences, mashhad, islamic republic of iran h festenstein

in this study, we have investigated the proliferative response of human dermal fibroblasts isolated from normal and psoriatic individuals to different cytokines. we found that il-1, tnf (α) and egf are stimulatory whereas ifn « and 1 both showed inhibitory activity on fibroblast proliferation. il-6 a more recently described cytokine, showed no detectable effects on cell proliferation. investiga...

آل‌ صاحب ‌فصول, فرشته‌, عابد خجسته, مجید, غریب‌دوست, فرهاد, محمودی, محمد باقر, محمودی, مهدی, مصطفایی, شایان, گنجعلی خانی حاکمی, مزدک,

Background: Systemic sclerosis (SSc) is an autoimmune rheumatic connective tissue disease. In normal wound healing process, fibroblasts are activated, proliferated and involved in tissue repair, and then removed by apoptosis. In systemic sclerosis, patient’s fibrosis occurs when fibroblasts become resistant to apoptosis and secrete a large amount of collagen and other extracellular matrixes. As...

Journal: :iranian biomedical journal 0
سید رامین پژوم شریعتی seyed ramin pajoum shariati محمدعلی شکرگزار mohammad ali shokrgozar منوچهر وثوقی manouchehr vossoughi علی اسلامی فر ali eslamifar

background: extensive full-thickness burns require replacement of both epidermis and dermis. in designing skin replacements, the goal has been to re-create this model and make a product which has both essential components. methods: in the present study, we developed procedures for establishing confluent, stratified layers of cultured human keratinocytes on the surface of modified collagen-chito...

Journal: :مجله دانشگاه علوم پزشکی شهید صدوقی یزد 0
سوسن صادقیان s sadeghian . [email protected] محمد حسین نصر اصفهانی mh nasr esfahani مسعود وطنی m vatani

introduction: in orthodontic therapy ,different materials are used and their presence in oral cavity may modify their properties. the purpose of this study was to evaluate the direct and indirect biocompatibility of three orthodontic composite resins on culture of human oral fibroblasts. methods: this was an interventional experimental study. the biocompatibility of three orthodontic composite ...

Journal: :iranian journal of allergy, asthma and immunology 0
mohammad reza khorramizadeh reza falak mohammad pezeshki farnaz safavifar parvin mansouri aziz ghahary

this study was conducted to examine if allergic contact dermatitis (acd) alters the expression of mmps in human dermal fibroblasts. fibroblasts are the primary source for mmp and matrix production in skin. mmps are known to involve in a number of physiological and pathological processes. some published data indicated a gelatinase-like activity in acute and chronic phases of allergic contact der...

Journal: :Chronic Diseases and Translational Medicine 2023

Induced pluripotent stem cell (iPSC) technology is one of the de novo approaches in regeneration medicine and has led to new research applications for wound healing recent years. Fibroblasts have attracted wide attention as first line used differentiation into iPSCs. Researchers found that fibroblasts can be induced different types cells variable mediums or microenvironments. This indicates pot...

Background: Many physical and mechanical phenomena occur during the acupuncture and tuina regime, and pressure is one of the most basic mechanical phenomena. Objectives: To understand the cellular bio-physical mechanism of basic mechanical stimulation via acupuncture and tuina by investigating the effect of different in vitro pressures on the cel...

HR Soleimanpour Lichaei S Esmaeilzadeh Bahabadi S Soleimanpour Lichaei,

Background The piwi family genes are highly conserved during evolution and play a crucial role in stem cell self-renewal, gametogenesis, and RNA interference in diverse organisms ranging from Arabidopsis to humans. Piwil2, also known as Hili, is one of the four human homologues of piwi. Piwil2 was found in germ cells of adult testis, suggesting that this gene functions in spermatogonial stem ce...

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