Infection-induced preterm birth is the largest cause of infant death and of neurological disabilities in survivors. Silibinin, from milk thistle, exerts potent anti-inflammatory activities in non-gestational tissues. The aims of this study were to determine the effect of silibinin on pro-inflammatory mediators in (i) human fetal membranes and myometrium treated with bacterial endotoxin lipopoly...

background: rupture of fetal membranes can occur at any gestational age. premature rupture of membranes (prom) means rupture of fetal membranes before the onset of labor. objective: the purpose of this study was to evaluate and compare the reliability of the vaginal washing fluid urea and creatinine for the diagnosis of prom and to determine cut-off values. materials and methods: a total of 179...

We examined the subcellular localizations of NAD(P)H oxidase, a reactive oxygen species (ROS)-producing enzyme, in fetal membrane chorion laeve trophoblasts from preterm or term pregnant women with or without chorioamnionitis (CAM). Ultrastructural enzyme histochemistry for NAD(P)H oxidase was used. In fetal membranes without CAM, approximately one quarter of the chorion laeve trophoblasts (25....

In 40 cases, microscopic studies have shown that early rupture of the fetal bladder is explained by anatomical structure membranes, which in such cases present signs either inflammation, degeneration, or underdevelopment their various layers.

Serum progesterone and estradiol-17β levels were estimated in Nili Ravi buffaloes (n=190) with and without fetal membranes retention in three agro-ecological zones of Punjab. The results showed that serum progesterone concentration was significantly higher (P<0.05) in buffaloes with retention of fetal membranes (RFM) compared to buffaloes without retention of fetal membranes (NRFM). The compari...

OBJECTIVE Spontaneous preterm birth (PTB) and preterm prelabor rupture of membranes (pPROM) are major pregnancy complications often associated with a fetal inflammatory response. Biomolecular markers of this fetal inflammatory response to both infectious and non-infectious risk factors and their contribution to PTB and pPROM mechanism are still unclear. This study examined fetal membrane produc...

Both simian virus 40 (SV40)-induced viral oncogenesis and the transplantation of SV40-transformed tumor cells in ham sters can be prevented by the immunization of animals with intact fetal cells from primiparous females. The fetal determi nants responsible for inducing transplantation resistance are temporally expressed on the surface of intact embryonic cells through the 11 th day of gestation...

Both simian virus 40 (SV40)-induced viral oncogenesis and the transplantation of SV40-transformed tumor cells in ham sters can be prevented by the immunization of animals with intact fetal cells from primiparous females. The fetal determi nants responsible for inducing transplantation resistance are temporally expressed on the surface of intact embryonic cells through the 11 th day of gestation...

Rupture of the fetal membranes is a common, but potentially serious complication of invasive fetal procedures. Quintero described a technique to seal the fetal membrane defect by means of a bloodpatch, usually called 'amniopatch' in this application. The successful use in two consecutive patients with ruptured membranes after a fetoscopic intervention at respectively 17 and 22 weeks' gestationa...