نتایج جستجو برای: extracellular matrices
تعداد نتایج: 198065 فیلتر نتایج به سال:
Latent TGF-beta binding proteins (LTBPs) are components of the extracellular matrix (ECM). They belong to the fibrillin/LTBP-superfamily, and are high molecular weight glycoproteins characterized by EGF-like repeats and 8-Cys repeats. Most LTBPs associate with the small latent forms of TGF-beta. Their roles include to facilitate the secretion of latent TGF-beta and to target it to the ECM. In o...
The physiology of glomerular filtration remains mechanistically obscure despite its importance in disease. The correspondence between proteinuria and foot process effacement suggests podocytes as the locus of the filtration barrier. If so, retained macromolecules ought to accumulate at the filtration barrier, an effect called concentration polarization. Literature data indicate macromolecule co...
THE FORM and function of the heart are the final result of an integration of cells, tissues, and extracellular material. The structure of many extracellular macromolecules is known, but studies of the cardiac extracellular matrix are still inadequate to provide a comprehensive understanding of it. The purpose of this review is to summarize the present knowledge of the cardiac extracellular matr...
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