Scientific advances in the creation of restorative biomaterials, in vitro cell culture technology, tissue grafting, tissue engineering, molecular biology and the human genome project provide the basis for the introduction of new technologies into dentistry. Non-vital infected teeth have long been treated with root canal therapy (for mature root apex) and apexification (for immature root apex), ...

The treatment of pulp in teeth with incomplete apex formation is still a clinical challenge. In addition to the most widely used medication for this purpose, calcium hydroxide, other materials have also been tested. Following the use of synthetic biomaterials for restoring bone tissue, and considering their recognized biocompatibility and bioconductivity, our intention was to explore the possib...

One of the most revolutionary materials introduced in Endodontics was the Mineral Trioxide Aggregate (MTA). The investigations regarding MTA formulation allowed researchers to disclose the composition and also some clinical problems related to the clinical application of this material. The augmentation on MTA’s studies resulted in the development a new generation of Endodontic materials, the ca...

Introduction. This paper describes a case of bone augmentation with combination of Platelet-Rich Fibrin (PRF) and β-TCP for treatment of chronic periapical cyst. The case was followed for 12 months. Methods. Patient presented with chronic periapical lesion in maxillary anterior teeth with history of trauma 8 years back. Radiographically, a periapical cyst was seen in relation to maxillary left ...

Recent advances in biomaterial science and tissue engineering technology have greatly spurred the development of regenerative endodontics. This has led to a paradigm shift in endodontic treatment from simply filling the root canal systems with biologically inert materials to restoring the infected dental pulp with functional replacement tissues. Currently, cell transplantation has gained increa...

introduction: the aim of this in vitro study was to evaluate the effect of calcium hydroxide (ch) on push-out bond strength of white mineral trioxide aggregate (wmta) and calcium-enriched mixture (cem) cement in simulated furcation perforations. methods and materials: furcation perforations, measuring 1.3 mm in diameter and 2 mm in height, were created in 80 human mandibular first molars. the t...

background and aims. biocompatibility of root-end filling materials is a matter of debate. the aim of this study was to compare the biocompatibility of a variety of commercial proroot wmta cements and a resin-based cement (geristore®) with different ph values of setting reaction and different aluminum contents, implanted into the subcutaneous connective tissue of rats at various time intervals....

OBJECTIVES The purpose of the study was to evaluate human dental pulp response to pulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calcium enriched mixture (CEM) cement. MATERIALS AND METHODS A total of nine erupted third molars were randomly assigned to each pulpotomy group. The same clinician performed full pulpotomies and coronal restorations. The patients were ...