Genes within the major histocompatibility complex (MHC) encode proteins involved in innate and adaptive immune responses. Genetic variation in this region can influence the immune response of an individual animal to challenges from a variety of pathogens; however, a complete documentation of genetic variation in the MHC is lacking for most domestic animals, including horses. To provide addition...

Numerous wireless sensor network algorithms assume that individual sensors possess location information. However, state of the art localization algorithms often achieve acceptable performance only under restrictive assumptions. For instance, some algorithms necessitate regular sensor deployment or centralized computations. Other algorithms require a high proportion of position aware nodes or th...

Measures of teachers’ “value added” to student achievement play an increasingly central role in k-12 teacher policy and practice, in part because they have been shown to predict teachers’ long-term impacts on students’ life outcomes. However, little research has examined variation in the long-term effects of teachers with similar value-added performance. In this study, we investigate variation ...

OBJECTIVES To determine whether early life adversity (ELA) was predictive of inflammatory markers and to determine the consistency of these associations across racial groups. METHODS We analyzed data from 177 African Americans and 822 whites aged 35 to 86 years from two preliminary subsamples of the Midlife in the United States biomarker study. ELA was measured via retrospective self-report. ...

Numerous wireless sensor network algorithms assume that individual sensors possess location information. However, state of the art localization algorithms often achieve acceptable performance only under restrictive assumptions. For instance, some algorithms necessitate regular sensor deployment or centralized computations. Other algorithms require a high proportion of position aware nodes or th...

Low molecular weight heparin (LMWH) has a structure similar to heparan sulfate, which exerts anti‑inflammatory effects via inhibiting elastase (Ela) activity. Release of Ela along the glomerular capillary wall may induce glomerular injury and proteinuria. The present study aimed to investigate the influence of LMWH on steroid‑sensitive nephrotic syndrome (SSNS) and the potential underlying mech...

Elastase activities were investigated in bronchoalveolar lavage (BAL) cells from healthy controls (C, n = 8) and patients with untreated mediastinopulmonary sarcoidosis at different stages: I (n = 5), II (n = 7), IIIA (n = 3), IIIB (n = 4). Elastase activities (EA and ELA) were measured against a synthetic substrate, succinyl-trialanine-paranitroanilide (SLAPN) and radiolabelled ligamentum nuch...

Haemolytic substances produced by ichthyotoxic algae often are unknown in molecular structure or specific mechanism of toxicity. Detection and quantification of such substances are dependent on bioassays, using markers that are sensitive for haemolytic impairment and generation of a recordable response. The erythrocyte lysis assay (ELA) represents an advantageous bioassay in this respect, becau...

Human ELA consists of three exons on chromosome 4, which generates a transcript (AK092578) that is annotated as a non-coding RNA. However, Chng et al. [1] has found that this gene contains a conserved open reading frame predicted to express a conserved vertebrate protein of 54 amino acids (aa) consisting of a secretory signal and a mature 32-aa peptide, which was called as ELABELA (ELA). The se...

Glacier variation is one of the best indicators of climate change in mountainous environment. In French Alps, many temporal data are acquired by glaciologists at glaciers scale: geometrical parameters (surface area, thickness, length and front altitude) are surveyed since the end of the 19th century. Those parameters are necessary to estimate the mass-balance of glaciers and, then, an accurate ...