Several new fluorescence malaria in vitro drug susceptibility microtiter plate assays that detect the presence of malarial DNA in infected erythrocytes have recently been reported, in contrast to traditional isotopic screens that involve radioactive substrate incorporation to measure in vitro malaria growth inhibition. We have assessed and further characterized the malaria SYBR Green I-based fl...

Abstract Background Endometrial cancer is an invasive gynecological prevalent in the world. The pathogenesis of endometrial related to multiple levels regulation, referring oestrogen, tumor-suppressor gene (e.g. PTEN ) or microRNAs miR-23a and miR-29b). Metapristone a hormone-related drug, which widely used clinical treatment cancer. However, underlying regulatory mechanism metapristone on stil...

OBJECTIVE Although 2 widely used susceptibility assays have been developed, their precision and sensitivity have not been assessed. DESIGN AND METHODS To assess the precision of the Antivirogram and PhenoSense assays, we examined susceptibility results of HIV-1 isolates lacking drug resistance mutations and containing matching patterns of drug resistance mutations. To assess sensitivity, we d...

On 17 November 2020, the United States Food and Drug Administration (FDA) authorized first rapid SARS-CoV-2 assay that can be run entirely at home [1]. Created by Lucira Health, All-In-One ...

Diabetes mellitus is a metabolic disorder characterized by high blood glucose level in the body. It occurs due to inadequate amount of insulin secreted body or resistance receptors. In present study, Baicalein flavone glycoside was evaluated for its effect on alpha-amylase and alpha-glucosidase enzymes using in-vitro assays extracting respective from whole wheat barley combination with in-silic...

objective(s): this paper aims to investigate synergistic inhibition of polysaccharide from sepia esculenta ink (sip), a newly isolated marine polysaccharide in our laboratory, on breast cancer mda-mb-231 cells exposed to cisplatin. materials and methods: cell viability of mda-mb-231 cells was determined by cck 8 assay. median-effect concentration was analyzed using chou-talalay method that was ...

Objective(s): This paper aims to investigate synergistic inhibition of polysaccharide from Sepia esculenta ink (SIP), a newly isolated marine polysaccharide in our laboratory, on breast cancer MDA-MB-231 cells exposed to cisplatin. Materials and Methods: Cell viability of MDA-MB-231 cells was determined by CCK 8 assay. Median-effect concentration was analyzed using Chou-Talalay method that was ...