The use of charge-coupled devic[; structures for analog signal processing is described. By operating in the charge domain, such structures offer the advantages of low··power, compact-layout, and high-speed operation. The circuits are digitally programmable and unlike continuous-time analog circuits, their operation can be fully synchronous. The application or the charge-domain circuits to on-ch...

Neuromyelitis optica or Devic`s disease is an inflammatory disimmune-neurodegenerative characterized by a progressive course, predominantly affecting the optic nerves and spinal cord, with relatively intact brain structures. The differential diagnosis of neuromyelitis multiple sclerosis based on identification typical clinical tomographic picture presence high level antibodies to aquaporin 4 in...

Results A total of 210 (161 females, 49 males) SLE patients were indentified, 39 of which had manifestations of potential CNS involvement and underwent imaging of their CNS including spinal cord. Three were indentified with probable Devic syndrome, which was confirmed in two (0.9%). Both patients were adolescent females and of Caucasian origin. In one patient NMO was the first manifestation of ...

BACKGROUND Myasthenia gravis (MG) and neuromyelitis optica (NMO, also known as Devic disease) are rare autoimmune disorders, with upper-limit prevalence estimates in the general population of 15 per 100,000 and 5 per 100,000, respectively. To our knowledge, an association between these diseases has not been previously reported. OBJECTIVES To describe 4 patients with MG who developed NMO after...

Chairman: Y. Thomassen (Norway); Members: J. Aaseth (Norway); G. Alfthan (Finland); D. Behne (FRG); H. A. Das (Netherlands); H. T. Delves (UK); R. M. Griffin (USA); M. Ihnat (Canada); V. Iyengar (FRG); 0. A. Levander (USA); Mirna Mikac-Devic (Yugoslavia); J. Pikkarainen (Finland); Marion F. Robinson (New Zealand); M. Stoeppler (FRG); Christine D. Thomson (New Zealand); R. T. Tulley (USA); C. Ve...

The conti nued scali ng of integ rated circu it techn ology at its curre nt Moore s Law rate could lead to circu its conta ining over a billi on trans istors with 20 nanom eter featu res by the year 2015. While the progr ess in elect ronics thus far has relie d on the scali ng of trans istors and on an incre asingly compl ex maze of inter connecting wires , futur e circu itry will requi re a ma...