Three strains of Aedes aegypti mosquitos viz (i) CRS, refractory to Chikungunya (CHIK) virus by oral route of infection but susceptible to DDT (2) CSS, susceptible to CHIK virus and also susceptible to DDT (3) CSS-DDTR, susceptible to CHIK virus but resistant to DDT, were examined for the effect of sublethal dosages of DDT and deltamethrin on their fecundity. Biochemical analysis showed that th...

The increased transcription of the Cyp6g1 gene of Drosophila melanogaster, and consequent resistance to insecticides such as DDT, is a widely cited example of adaptation mediated by cis-regulatory change. A fragment of an Accord transposable element inserted upstream of the Cyp6g1 gene is causally associated with resistance and has spread to high frequencies in populations around the world sinc...

One DDT-contaminated soil and two uncontaminated soils were used to enumerate DDT-resistant microbes (bacteria, actinomycetes and fungi) by using soil dilution agar plates in media either with 150 mg DDT ml−1 or without DDT at different temperatures (25, 37 and 55◦C). Microbial populations in this study were significantly (p<0.001) affected by DDT in the growth medium. However, the numbers of m...

Glutathione S transferases (GSTs) are multifunctional enzymes involved in detoxification of xenobiotic compounds in majority of the insect groups. Significance of insect GSTs is their elevated level of activity in association with insecticide resistance. This investigation was to explore the metabolic status of GSTs in two Indian DDT-resistant malaria vectors, Anopheles culicifacies and Anophel...

The dehydrochlorination of 1 , 1 , I-trichloro-2,2-bis(p-chlorophenyl)ethane to its nontoxic, ethylenic analogue, DDE,* by extracts of DDT-resistant houseflies (1Musca domestica) was first demonstrated by Sternburg et al. (I). It was shown that this system was GSH-dependent and that no DDT dehydrochlorinase could be detected in DDT-susceptible flies by the means then available. The titer of DDT...

Sonitpur district, Assam (India) is well known for malaria incidence since many years. The extensive use of insecticides for the control of malaria and other vector species is being carried out for vector management. The insecticide resistance status of Aedes albopictus (Diptera: Culicidae) to DDT (dichloro-diphenyl-trichloroethane) and deltamethrin was studied in the Sonitpur district of Assam...

Adaptation of insect phenotypes for survival after exposure to xenobiotics can result from selection at multiple loci with additive genetic effects. To the authors' knowledge, no selective sweep analysis has been performed to identify such loci in highly dichlorodiphenyltrichloroethane (DDT) resistant insects. Here we compared a highly DDT resistant phenotype in the Drosophila melanogaster (Dro...

Intense and persistent use of DDT for malaria control has increased resistance and induced exophilic behavior of Anopheles pseudopunctipennis. An evaluation of bendiocarb and DDT to control this species in Sinaloa, Mexico, showed that, in spite of DDT-resistance, both insecticides produced similar effects. Feeding patterns were analyzed to explain these results. Resting mosquitoes were collecte...

glutathione s-transferases (gsts) are a major family of detoxification enzymes which possess a wide range of substrate specificities. interest in insect gsts has primarily focused on their role in insecticide resistance. in this study, following world health organization (who) routine susceptibility test, dna was extracted from specimens of anopheles stephensi collected from the kazeroon distri...