نتایج جستجو برای: cns tumor
تعداد نتایج: 526872 فیلتر نتایج به سال:
background: tumors of the central nervous system (cns) are a heterogeneous group of neoplasms with different prevalence in different sex and age groups and various parts of cns. objectives: determining the relative frequency of different types of cns tumors in different ages, sex and cns anatomical locations. materials and methods: this retrospective study was performed using pathological repor...
in 1890, coley observed that cancer patients who developed infections had smaller tumors. from this, he developed coley’s toxin and treated tumors with injections of infectious materials. in 1960s, mahaley used monoclonal antibodies to treat central nervous system(cns) tumors, that research and clinical investigations in brain tumor immunotherapy became a serious undertaking. there are severa...
The efficacy of immunotherapeutic TLR7/8 activation by resiquimod (R848) was evaluated in vivo, in the CNS-1 rat glioma model syngeneic to Lewis rats. The immune treatment was compared with cytotoxic cyclophosphamide chemotherapy, and as well, was compared with the combination cytotoxic and immunotherapeutic treatments. We found that parenteral treatment with the TLR7/8 agonist, resiquimod, eve...
Abstract BACKGROUND Breast cancer is the most common in world and second to metastasize central nervous system (CNS). CNS-metastases are type of brain tumor have a rising incidence. They associated with neurologic morbidity mortality remain major clinical challenge. Survival withCNS-metastases short median survival order months. The incidence 5.1% breast however true prevalence not known; at au...
In this chapter, we propose a novel algorithm for characterizing a variety of CNS tumors. The proposed algorithm is illustrated with an analysis of an Affymetrix gene expression data from CNS tumor samples (Pomeroy et al., 2002). As discussed in the previous chapter entitled: CNS Tumor Prediction Using Gene Expression Data Part I, we used an ANOVA model to normalize the microarray gene expressi...
Abstract Background The clinical, morphological, molecular features, treatment modalities, and survival of primary central nervous system neuroblastoma ganglioneuroblastoma (CNS-NB CNS-GNB) in adult patients are still poorly understood. Material Methods study included 15 with CNS-NB 16 CNS-GNB aged 18 years older who were treated our clinic from 2008 to 2020. Clinical, radiological data surgica...
Primary CNS lymphoma is an aggressive form of non-Hodgkin lymphoma whose growth is restricted to the central nervous system. We used cDNA microarray analysis to compare the gene expression signature of primary CNS lymphomas with nodal large B-cell lymphomas. Here we show that while individual cases of primary CNS lymphomas may be classified as germinal center B-cell, activated B-cell, or type 3...
Background: In this study, we examined the epidemiologic characteristics of childhood brain tumors in patients referred to MAHAK Pediatric Cancer Treatment and Research Center (one of the main national referral centers for childhood malignancies in Iran) for treatment. Materials and Methods: This cohort (simple sampling) study consisted of 198 children less than 15 year old with CNS tumor ref...
In 1890, Coley observed that cancer patients who developed infections had smaller tumors. From this, he developed Coley’s toxin and treated tumors with injections of infectious materials. In 1960s, Mahaley used monoclonal antibodies to treat central nervous system(CNS) tumors, that research and clinical investigations in brain tumor immunotherapy became a serious undertaking. ...
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