Varicocele is the most common cause of infertility in men. The mechanism by which varicocele cause the variable effect on male infertility and is still unknown. Varicocele is found in 35 to 81 % of infertile men, and is one treatable form of male infertility. Although many advances have occurred in the treatment of varicocele, it still represents an important and challenging aspect of basic res...

Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility. Significant study has clarified the negative impact of varicocele on semen parameters and more recent work has shed light on its detrimental effects on the molecular and ultrastructural features of sperm and the ...

Varicocele affects approximately 35%-40% of men presenting for an infertility evaluation. There is fair evidence indicating that surgical repair of clinical varicocele improves semen parameters, decreases seminal oxidative stress and sperm DNA fragmentation, and increases the chances of natural conception. However, it is unclear whether performing varicocelectomy in men with clinical varicocele...

Varicocele is often cited as the most common cause of male factor infertility. Arguments in support of this statement include reports of increased prevalence of varicocele in populations of infertile men compared with fertile or otherwise unselected men, association of varicocele with abnormal semen parameters, and improvements in semen parameters and/or pregnancy rates after varicocele repair....

Male factor infertility often happened in patients with varicocele and genetic disorder. Microsurgical varicocele is the most effective and safe treatment option for male infertility in patients with varicocele. Y chromosome microdeletions and chromosomal abnormalities are the two types of genetic disorder. Now we could use commercial detection kits through PCR amplification of selected regions...

Male factor infertility often happened in patients with varicocele and genetic disorder. Microsurgical varicocele is the most effective and safe treatment option for male infertility in patients with varicocele. Y chromosome microdeletions and chromosomal abnormalities are the two types of genetic disorder. Now we could use commercial detection kits through PCR amplification of selected regions...

Background: Reactive oxygen species (ROS) are a group of free radicals that in excessive amounts have negative influence on sperm quality and function. Objective: To study the effect of varicocele and its severity on the level of ROS in infertile men with clinical varicocele. Materials and Methods: In this controlled prospective study, 42 men with clinically diagnosed left varicocele and 30 fer...

PURPOSE To evaluate the association between varicocele and MPV values in pediatric and adult patients. And its association with different clinical parameters. MATERIALS AND METHODS We retrospectively analyzed the medical charts of patients treated for varicocele at our Institution between December 2010 and December 2014. The study patients were divided into three groups: group 1- patients wit...

OBJECTIVE To evaluate semen parameters in infertile Saudi Arabian men. METHODS In this retrospective study, semen analysis and other clinical data were extracted from medical records of men attending an infertility clinic. Patients were stratified according to smoking status and presence or absence of varicocele. RESULTS The study included 425 patients. Nonsmokers (n = 322) had significantl...

To establish the extent of varicocele as the cause of infertility in men and compare the various techniques of treatment. We searched PubMed and the Cochrane Library database using varicocele, male infertility, varicocelectomy as keywords. Varicocele seems to be a growing problem considered to be one of the most common causes of male infertility in recent times. Nevertheless, its role remains u...