Cerebral stroke is a leading cause of serious disability and is the third leading cause of death in most countries and its prevention is a key to reduction of morbidity, mortality, and disability. This study investigated the relationship between hyperlipidemia (cholesterol and triglyceride), polycythemia, and incidence of cerebral stroke. Data was obtained from 70 participants that hospitalized...

Cerebral stroke is a leading cause of serious disability and is the third leading cause of death in most countries and its prevention is a key to reduction of morbidity, mortality, and disability. This study investigated the relationship between hyperlipidemia (cholesterol and triglyceride), polycythemia, and incidence of cerebral stroke. Data was obtained from 70 participants that hospitalized...

Objective(s) Previous studies have demonstrated that pretreatment with alpha-tocotrienol (a-TCT) can reduce ischemic damage in mice following middle cerebral artery (MCA) occlusion. It is also reported to decrease stroke- dependent brain tissue damage in 12-Lox-deficient mice and spontaneously hypertensive rats. In the present study, the neuroprotective effects of a-TCT and rosiglitazone (RGZ)...

to minimize the risk of embolic events, several protection strategies have been introduced. we have evaluated the short-term outcome of patients who underwent carotid stenting with the routine use of cerebral protection devices. in our center, 36 successful carotid stenting procedures (of 38 attempted) were performed in 37 patients (23 men; age mean [sd] 667 years). cerebral protection involv...

Cardiac diseases are common post-stroke and are associated with increased morbidity and mortality. One possible mechanism of acute cardiac injury is the neurogenic myocardial damage, where the cerebral injury is disturbing the normal sympathetic and parasympathetic neuronal outflow to the heart leading to cardiac damage including myocardial infarctions. The exact mechanism is not completely und...

increased levels of proinflammatory cytokines have been recorded after the onset  of transient  or  permanent  brain  ischemia and  are  usually associated with  exacerbation  of ischemic injury. embolic stroke model is more relevant to the pathophysiological situation in such  patients, because the  majority of  ischemic injuries in humans  are induced  by old thrombi that originate from the h...

Background: Hyperthyroidism as a risk factor for stroke is not conclusive. There are no definite data on the relationship between ischemic cerebrovascular injury and hyperthyroidism. This study was designed to define whether the outcomes of post-ischemic stroke injury are influenced by chronic hyperthyroidism. Methods: Two groups of hyperthyroid (HT) and control euthyroid rats of equal numbers ...

Background: Previous studies show that serum level of uric acid is significantly correlated with mortality and functional outcome in patients with ischemic stroke and according to some other studies, ischemic stroke is associated with stenosis of some stenoisis of somespecific brain vessels. The aim of this study was to investigate the frequency of hyperuricemia and its associa...

Introduction: Arterial hypertension is one of the causes of stroke, and as one of the vasculotoxic conditions intensifies ischemic stroke complications. The aim of the present study was to analyze the effects of short-term cerebral hypertension on ischemia/reperfusion injury and pathogenesis of ischemic stroke. Methods: The experiments were performed on three groups of rats (N=36) Sham, cont...

background: clinical information about stroke in the vertebrobasilar territory has lagged behind that for anterior circulation syndrome. this is the first report from posterior circulation syndrome registry in iran.   methods: consecutive patients with brain infarction in vertebrobasilar territory admitted to ghaem hospital, mashhad were enrolled in a prospective study during 2006-2007. diagnos...