PNEUllOTHORAX DE L'ENFANT  Presentation de 17 cas. Revue de la litterature Par: Marandian M.H., Momenzadhe A., Wali­zade G., Kabiri M., A'skari H. et Movasat M.  Durant deux ans et demi, 17 cas de pneumo­thorax ont ete observes dans le service de Pedia­trie de !'Hospital Pahlavi de l'Univm-site de Teheran:  1)9 de ces malades etaient ages de moins d'un an. Le malade le plus age atteint de pn...

Serum cystyl aminopeptidase (CAS) activity was estimated at 36 weeks' gestation in 209 normotensive pregnancies. The highest activity was found in 31 women who had spontaneous deliveries before 38 weeks' gestation and the lowest in 76 women who were induced after term. The enzyme levels in 117 women who developed hypertension of pregnancy were higher than for normotensives; the highest levels w...

Aquatic microalgae have evolved diverse CO2-concentrating mechanisms (CCMs) to saturate the carboxylase with its substrate, to compensate for the slow kinetics and competing oxygenation reaction of the key photosynthetic CO2-fixing enzyme rubisco. The limiting CO2-inducible B protein (LCIB) is known to be essential for CCM function in Chlamydomonas reinhardtii To assign a function to this previ...

Carbonic anhydrase (CA) is a zinc enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate (hydrogen carbonate) and a proton. CAs have been extensively investigated owing to their involvement in numerous physiological and pathological processes. Currently, CA inhibitors are widely used as antiglaucoma, anticancer and anti-obesity drugs and for the treatment of neurologic...

The interaction of viruses and their prokaryotic hosts shaped the evolution of bacterial and archaeal life. Prokaryotes developed several strategies to evade viral attacks that include restriction modification, abortive infection and CRISPR/Cas systems. These adaptive immune systems found in many Bacteria and most Archaea consist of clustered regularly interspaced short palindromic repeat (CRIS...

Background: Carotid artery stenting (CAS) has recently been recommended as an alternative to carotid endarterectomy (CEA) by some clinicians. Objective: This study was designed to evaluate the success rate and in-hospital and 30-day adverse events in our first experiences in Iran for CAS with protection devices, to document our results and guide further use of CAS. Methods: From December 2...

To conform to the multiple regulations of triterpene biosynthesis, the gene encoding farnesyl pyrophosphate synthase (FPS) was transformed into Panax notoginseng (P. notoginseng) cells in which RNA interference (RNAi) of the cycloartenol synthase (CAS) gene had been accomplished. Transgenic cell lines showed both higher expression levels of FPS and lower expression levels of CAS compared to the...

•Cryo-EM structure of Cas12f in complex with a guide RNA and its target DNA•Type V-F effector consisting dimer single RNA•Molecular mechanism the RNA-guided DNA cleavage by miniature Cas12f•Evolutionary insights into possible origin type V CRISPR-Cas enzymes endonucleases derived from adaptive immune systems are widely used as powerful genome-engineering tools. Among diverse nucleases, (also kn...

Bacteria and Archaea encode clustered, regularly interspaced, short palindromic repeat (CRISPR) systems to confer adaptive immunity to invasive viruses and plasmids. Recent studies of CRISPR systems revealed that diverse CRISPR-associated (Cas) interference modules often coexist in different organisms but functions of cas genes have not been dissected in any of these systems. The crenarchaeon S...

Sur 2601 admissions, chez 113 enfants at­teints de la maladie de Bouillaud, hospitalises en cinq ans dans deux services de pediatrie de Te­heran (C.H.U. de Pahlavi, C.H.U. de Logman­doleh Adham) 6 cas de manifestations cutanees  (trois cas de nodules, trois cas d'erytheme mar­ginatum) ont ete constates, trois d'entre eux souffrant d'une cardite severe et evolutive.  En Iran !'incidence des si...