Objective(s): Staphylococcus epidermidis is a common cause of medical device-associated infections due to biofilm formation, and its elimination is extremely challenging. Although rifampin efficacy against S. epidermidis biofilms has been confirmed, its use as a single agent may lead to resistance. As such, it is assumed that the combination of rifampin and N-acetylcysteine (NAC) could exert ad...

Biofouling of membranes demands costly periodic cleaning and membrane replacement. A sustainable and environmentally friendly solution for maintenance is not available and would be of great interest for many purposes including economical. As complex biofilm formation by environmental strains is the major cause of biofouling and biofilm formation in most cases are controlled by N-Acylhomoserine ...

Biofilms transform independent cells into specialized cell communities. Here are presented some insights into biofilm formation ascertained with the best-characterized strain, Escherichia coli. Investigations of biofilm formation and inhibition with this strain using whole-transcriptome profiling coupled to phenotypic assays, in vivo DNA binding studies and isogenic mutants have led to discover...

Background: Paenibacillus larvae is the etiological agent of American foulbrood (AFB) disease, the most lethal disease in honeybee (Apis mellifera) larvae. Aims: The aim of the present work was to study the antimicrobial effect of cell free supernatant (CFS) of probiotics on an Iranian isolate’s biofilm formation. Methods: A l...

Background and objectives: Quercus brantii subsp. persica is used in folk medicine to treat infections in Iran. There is not available report on the anti-biofilm activity of Quercus brantii subsp.  persica. The aim of the present study was to investigate the effects of Quercus brantii subsp. persica against...

conclusions minimum biofilm eradication values of ciprofloxacin obtained in the study are close to the values of the minimal inhibition concentration (mic). results all tested strains formed a biofilm. a value of 1.0 μg/ml ciprofloxacin is mbe50 for the strains of both tested species. an mbe90 value of ciprofloxacin for isolates of p. vulgaris was 2 μg/ml and for p. mirabilis was 512 μg/ml. mat...

Nosocomial infections and increasing multi-drug resistance caused by Acinetobacter baumannii have been recognized as emerging problems worldwide. Moreover, A. baumannii is able to colonize various abiotic materials and medical devices, making it difficult to eradicate and leading to ventilator-associated pneumonia, and bacteremia. Development of novel molecules that inhibit bacterial biofilm fo...

background : incidence of  white  spots due  to  demineralization of  enamel  and  gingival problems  is  an  unacceptable  result  of  orthodontic  treatment.  plaque  accumulation  and bacterial biofilm growth are responsible for these phenomena. the resin-based dental composites used as bonding agents in orthodontics play a major role in mentioned problems. as recent researches assert the an...

Biofilm formation by Staphylococcus aureus represents a problem in both the medical field and the food industry, because the biofilm structure provides protection to embedded cells and it strongly attaches to surfaces. This circumstance is leading to many research programs seeking new alternatives to control biofilm formation by this pathogen. In this study we show that a potent inhibition of b...

use of herbal extracts and essences as natural antibacterial compounds has become increasingly popular for the control of oral infectious diseases. therefore, finding natural antimicrobial products with the lowest side effects seems necessary. the present study sought to assess the effect of punica granatum l. water extract on five oral bacteria and bacterial biofilm formation on orthodontic wi...