نتایج جستجو برای: bibr1532

تعداد نتایج: 22  

2015
Roula Tahtouh Anne-Sophie Azzi Nada Alaaeddine Soulaima Chamat Hasnaa Bouharoun-Tayoun Layal Wardi Issam Raad Riad Sarkis Najibe Abou Antoun George Hilal

Alpha-fetoprotein (AFP) is a diagnostic marker for hepatocellular carcinoma (HCC). A direct relationship between poor prognosis and the concentration of serum AFP has been observed. Telomerase, an enzyme that stabilizes the telomere length, is expressed by 90% of HCC. The aim of this study was to investigate the effect of telomerase inhibition on AFP secretion and the involvement of the PI3K/Ak...

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