Recent studies have proposed that a decline in bacterial infections such as tuberculosis is a factor underlying the rising prevalence and severity of atopic disorder in developed countries. There are conflicting ideas about the inverse relationship between BCG (Bacillus Calmette-Guerin) vaccination and asthma. Stronger response to tuberculin test as an indicator of more potent TH1 response is s...

OBJECTIVE This case control study was conducted to evaluate any association between the BCG scar size and occurrence of asthma among children between 6-14 years of age. METHODS Cases consisted of 90 asthmatic children. Control group included 90 non-asthmatic children from the emergency room service of the same hospital. The BCG scar was measured as the average of the transverse and longitudin...

Results: Coverage for BCG, OPV3, DPT3 & Measles were 92.04%, 85.23%, 83.71% & 82.20% respectively. BCG scar was seen in 83.95% of children out of those who received BCG. The proportions of fully immunized children were 79.55%. Unimmunized children were 4.16%. Dropout rate was 9.05% for BCG-DPT3, 10.69% for BCG-Measles & 7.53% for DPT1-DPT3. Compared to NFHS3 (2005-06) as well as DLHS3 (Gandhina...

The prevalence of atopic disease in recent decades has been dramatically increased. It has been suggested that BCG vaccination may protect against development of allergic diseases.The purpose of this study was to identifying relation between scar of BCG vaccine and atopy. This cross-sectional study was done in 1000 children, 10-15 years of age, in Zanjan city. One thousand children (501 girls a...

OBJECTIVE To study local reaction and to ascertain timing of scar formation in infants after BCG vaccination at birth, with and without simultaneous administration of trivalent OPV. DESIGN Prospective observational study. SETTING Teaching hospital in Lucknow, India. PARTICIPANTS 152 term neonates born in the hospital and given BCG and OPV 0-dose simultaneously before discharge, within 7 d...

OBJECTIVE To investigate the influence of BCG vaccination or revaccination on tuberculin skin test reactivity, in order to guide the correct interpretation of this test in a setting of high neonatal BCG vaccination coverage and an increasing BCG revaccination coverage at school age. METHODS We conducted tuberculin skin testing and BCG scar reading in 1 148 children aged 7-14 years old in the ...

BACKGROUND Oral polio vaccine (OPV) is recommended to be given at birth together with BCG vaccine. While we were conducting two trials including low-birth-weight (LBW) and normal-birth-weight (NBW) infants in Guinea-Bissau, OPV was not available during some periods and therefore some infants did not receive OPV at birth, but only BCG. We investigated the effect of OPV given simultaneously with ...

TB is widely prevalent in India. As disease surveys are too expensive and difficult, the assessment of TB situation in developing countries is preferably done by subjecting a representative sample of children without BCG scar to tuberculin testing. Prior to a tuberculin survey in school children of Bangalore city, a cluster sample, household survey was undertaken during SeptemberNovember 1995 w...

BACKGROUND Over the past four decades, the World Health Organization established the Expanded Programme on Immunization (EPI) to foster universal access to all relevant vaccines for all children at risk. The success of this program has been undeniable, but requires periodic monitoring to ensure that coverage rates remain high. The aim of this study was to measure the BCG vaccination coverage in...

Bacillus Calmette-Guérin (BCG), the most common vaccine worldwide, has broad effects on the immune system. Hookworm infections are a major source of morbidity. In response to a preliminary report of BCG vaccination protection against nematodes in human immunodeficiency virus-infected adults, data from an ongoing prospective study were analyzed to determine the intensity (eggs per gram of stool)...