Objective: Measurement of glomerular filtration rate (GFR) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. As extremely accurate methods of GFR measurement (i.e. Inulin clearance) are expensive and Time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the GFR measurement. Here we have ...

background: simvastatin is a widely used medication in cardiac care. here we evaluate the role of atp sensitive potassium (katp) channels in simvastatin induced renal protection after renal ischemia/reperfusion (i/r) injury.    methods: a total of 81 male wistar rats, were treated with simvastatin (10 and 20mg/kg/day gavage, one week). some groups received glibenclamide (katp channel inhibitor ...

three strains of nontypeable haemophilus influenzae namely nthi-i , nthi-ii and nthi-iii were isolated from the sputum of patients with bronchitis and identified by biochemical, serological and electron microscopy. the polypeptide patterns of isolates were compared and found to have similar sodium dodecyl sulphate-polyacrylamide gel electrophoresis (sds-page) polypeptide patterns, although some...

The dose dependence of mezlocillin pharmacokinetics was examined in relation to renal function after intravenous doses of 1 and 5 g in 16 subjects with various degrees of renal impairment. Dose and time-average model-independent physiological parameters were calculated from plasma concentration and urinary excretion data. Lack of superimposition of plasma concentration profiles occurred between...

one of the most prominent industries is bending, while using rotary draw bending method is known to be the most conventional approach for thin wall tube bending. pressure die is one effective tool which boosts the tube during the process and eventually improves the bending quality. other effective parameters are mandrel and the amount of clearance between tube and mandrel. in the present study,...

the purpose of this study was to determine the number of prescribed antibiotics being appropriately adjusted and to assess antibiotics with the highest incorrect dosing based on the patient’s renal function according to distinguished guidelines. the study was conducted at a 446-bed university hospital. one hundred and fifty patients admitted through different wards of the hospital were included...

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Tujuan penelitian ini untuk mengetahui pengaruh dari faktor pre clearance, custom dan post clearance baik secara parsial maupun simultan terhadap dwelling time peti kemas di pelabuhan Tanjung Priok, serta melihat manakah yang paling dominan dalam Priok. Data sekunder didapatkan Kantor Pelayanan Utama Bea Cukai Tipe A Priok sebagai data akan diolah ini. Kemudian analisis dengan metode regresi li...