Acute myeloid leukemia (AML) patients encounter complications mainly due to their underlying disease or chemotherapy. Although they are at high risk for both hemorrhagic and thrombotic complications, vascular complication as an initial manifestation is less common rarely reported, especially in non-acute promyelocytic (non-APML). A 58-year-old female with no co-morbidity presented fever, decrea...

Genetic and epigenetic events within a cell which promote a block in normal development or differentiation coupled with unregulated proliferation are hallmarks of neoplastic transformation. Differentiation therapy involves the use of agents with the ability to induce differentiation in cells that have lost this ability, i.e. cancer cells. The promise of differentiation-based therapy as a viable...

Retinoic acid syndrome is a novel complication of therapy with all-trans retinoic acid (ATRA) in patients with acute promyelocytic leukemia (APML). Primarily the syndrome consists of fever and respiratory distress. Additional features include weight gain, oedema over lower extremities, pleural or pericardial effusion and hypotension. We report electrophysiological changes in a 16 year old patie...

We propose an extension of the FML-APML specification to match our needs for specifying the communicative strategies of an engaging interactive toy. This intelligent toy uses various strategies defined in previous work to try to engage the child in a long-term relationship. We have identified several useful tags that are not yet incorporated in FML, in particular, tags to represent actions, emo...

Acute promyelocytic leukemia (APML) is considered to be sensitive to all-trans-retinoic acid (ATRA) which acts as a differentiating agent. ATRA is considered to be a well-tolerated agent and is known to achieve complete remission in acute promyelocytic leukemia. However, a few cases on long term all-trans-retinoic acid (ATRA) use can develop pseudotumor cerebri. Out of 32 patients with APML who...

! " # $ %!& $ ! ' )( * ! +*%, $ ./ 10 2 *" 3 &4&* 5 6 , % ! 64& ! *7 ! * 8 % . ! ," 9 '* , : ) ! ' ;%, '! < =*>! * ? @ , AB! * $ %!?4& ! *C % " " AD > ! "EGFH, < ) !? ? I J !@4H 6 ) ! KH L6 C $ M N9 O EQP2 < R S ) ! H* ) B $ 1!@O T#* 5 @ U ! ) 1 ) V $ ?4H W * W < ! B ! V! R %! ' , 1 X -! * % % < %! E+P2 ' O ) ?! X* W *%O% 1 2 % $ $ <! Y @ 3O(%. G *" 3 E:ZQ C A[O\! * XA[ $!R AW! * 7 ] $ , 6 G! *...

aging scan showed no abnormalities. Lumbar puncture showed an increased opening pressure (225 cm H2O), but the cerebrospinal fluid showed no cells, no hypoglycorrhachia, and no elevation in the protein concentration. Treatment with ATRA was discontinued, and the APML was treated with a combination of arsenic trioxide, daunorubicin hydrochloride, and cytosine arabinoside. Over the next 6 weeks, ...

30 Objectives: The principle aim of the current study was to examine within-match patterns of locomotor 31 efficiency in Professional Soccer, determined as the ratio between tri-axial accelerometer data 32 (PlayerLoad) and locomotor activities. Between match variability and determinants of PlayerLoad 33 during match play were also assessed. Design: A single cohort, observational study. Methods:...

LUCIA is an MPEG-4 facial animation system developed at ISTCCNR1. It works on standard Facial Animation Parameters and speaks with the Italian version of FESTIVAL TTS. To achieve an emotive/expressive talking head LUCIA was build from real human data physically extracted by ELITE optotracking movement analyzer. LUCIA can copy a real human by reproducing the movements of passive markers position...