نتایج جستجو برای: antacids
تعداد نتایج: 477 فیلتر نتایج به سال:
BACKGROUND Antacid treatments decrease the serum concentrations of first-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs), although it is unknown whether antacids affect clinical outcomes. As cerebrospinal fluid concentrations of TKIs are much lower than serum concentrations, we hypothesized that this drug-drug interaction might affect the prognosis of patien...
D is a purine nucleoside analog that is indicated for the treatment of human immunodeficiency virus (HIV) infection. It has been administered orallywith antacids toprotect against acid-inducedhydrolysis in the stomach. Formulations of didanosine that are currently available as buffered products or are intended to be used with buffer include the buffered powder for oral solution, chewable/disper...
Several antibiotics show significant pharmacokinetic interactions when they are given orally concomitantly with antacids. The objective of this study was to evaluate the effects of antacid (containing magnesium) on the pharmacokinetics of linezolid. A single dose of 600 mg linezolid was given orally alone and 10 min after administration of the antacid Maalox 70mVal, which contains 600 mg magnes...
BACKGROUND Oesophageal acid neutralization with antacids depends on the duration of oesophageal antacid exposure and acid neutralizing capacity. A gum that releases antacid as it is chewed could take advantage of both mechanisms to enhance heartburn relief. METHODS Twenty-four subjects were crossed over to four regimens: placebo, chewable antacid tablets (1000 mg CaCO3), lower dose gum (600 m...
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