Disease condition is one of the major factors which can affect the dose of a drug. This study was designed to compare the pharmacokinetic parameters of metronidazole in healthy volunteers and in patients suffering from amoebiasis and to recommend any modification of dose if required. The healthy volunteers were considered as Group A and the patients as Group B. Subjects from both groups were tr...

Counter immunoelectrophoresis using cellulose acetate as the supporting medium was used as a rapid screening test for amoebic abscess. All the sera from 40 cases gave positive results. No false positives were obtained, but the results in intestinal amoebiasis were less reliable. An attempt was made to account for discrepancies in previous reports.

Amoebic liver abscess is one of the forms invasive amoebiasis. With untimely treatment, this disease can be complicated by peritonitis, dissemination pathogen with development sepsis. This article presents a clinical case amoebic in patient V., 40 years old results biopsy examination surgical specimens

The role of macrophages in intestinal amoebiasis in mice has been investigated. The effect of injuring host macrophages on the course of infection was examined by using strains selected as being either genetically susceptible (C3H/HeJ, C57BL/6) or genetically resistant (A/J) to amoebiasis. Mice were treated with an intravenous injection of silica particles 1 day before infection with 2.5 X 10(5...

To correlate a particular state of immunity with Entamoeba spp., we used colorimetric PCR to differentiate E. histolytica from E. dispar in individuals with amoebiasis and to associate its presence with the clinical profile, including humoral and cellular immune responses to E. histolytica. Our results showed high levels of antibody in acute amoebiasis and elevation of IL-4 production, a cytoki...

Doshi JC. Amoebic granuloma: A review. Indian J Med Sci 1969;23:61-7. Peison B. .Acute localized amebic appendicitis: Report of a case. Dis Colon Rectum 1973:16:532-6. Anderson HH. Delpiat D. Weeks A. et al, Amoebiasis and pseudopolyposis of the coloti. JAMA 1958,167:212. Kannath L Judy. Amoebiasis presenting as an acute abdomen. Am JSurg 1974:127:275-9. Mahajan RC. Katariya RN. Kaushik SP. Amo...

The clinical presentation of amoebic colitis are diverse. Amoebiasis is comparatively rare in the U.K. and, unless the clinician is aware of the condition, wrong diagnosis often leads to delay in appropriate treatment resulting in high mortality. Diagnosis rests on clinical suspicion, stool examination, sigmoidoscopy with rectal biopsy and serological tests. Amoebiasis is readily treatable and ...