The aim of the present study was to investigate the effects of Mangifera indica leaves extract on the kidney function parameters in alloxan induced diabetic Swiss albino mice. Forty five albino mice (weighing 28 to 32 g) were randomly divided into control, alloxan treated and Mangifera indica treated mice group. Diabetes was induced in mice by injecting intraperitoneally alloxan monohydrate at ...

Many applied conventional drugs in treating diabetes have been reported to possess some drawbacks which necessitate a search for alternative therapies. In order more active antidiabetic agent, this study synthesized and evaluated properties of Mangifera indica crude extract its Cu (II) complex alloxan-induced diabetic albino rats. The leaf metal were characterized using percentage analysis IR s...

Objectives: This study investigated the antidiabetic and antihyperlipidemic potential of ethanol extract leaves stem Cissus gracillis on alloxan monohydrate-induced diabetic albino rats. Methods: Preliminary phytochemical screening acute toxicity were carried out. Animals assigned into seven groups five rats each. Groups A B administered 10 mg/kg each glibenclamide atorvastatin respectively, C,...

Objectives: Diabetes mellitusmanifests itself in a wide variety of complications and the symptoms of this disease are multifactorial. Previousstudies proved that this disease is directly related to hyperglycemia and hyperlipidemia. The aim of this study was to investigate the hypoglycemic and hypolipidemic effects of hydroalcoholic extract of Prangos frulacea (L.)Lindlin alloxan-induced diabeti...

Objectives: Diabetes mellitus is associated with biochemical, physiological and pathological alterations in the liver. The aim of this study was to investigate the effects of hydroalcoholic extract of Prangos ferulacea (L.) Lindle (P.f) on changes in rats´ liver structure and serum activities of alanin and aspartate aminotransferases after alloxan injection. Materials and Methods: In this stud...

With the various side effects associated with synthetic medicines for treating diabetes, there is a need to develop herbal remedies as an alternative. Although Spinacia oleracea L. leaves are used treat health conditions, including little research validate its antidiabetic properties. This study aimed investigate hypoglycemic and hypolipidemic effect of methanolic ethanolic extracts against all...

Nghiên cứu này nhằm mục đích đánh giá hoạt động chống đái tháo đường (ức chế α-glucosidase) và oxy hóa (trung hòa gốc tự do DPPH; tiềm năng khử sắt) in vitro của cao khô vỏ bưởi Năm Roi. Các tăng glucose huyết hạ lipid máu vivo Roi ở chuột đái tháo đường alloxan monohydrate gây ra đã được thực hiện. Cao có khả ức chế enzym α-glucosidase hóa. sử dụng liều lượng thích hợp 100, 200 400 mg/kg cho l...

This study was to create a long-term rabbit model of diabetes mellitus for medical studies of up to one year or longer and to evaluate the effects of chronic hyperglycemia on damage of major organs. A single dose of alloxan monohydrate (100 mg/kg) was given intravenously to 20 young New Zealand White rabbits. Another 12 age-matched normal rabbits were used as controls. Hyperglycemia developed w...

Aim: To evaluate the effect of Enalapril on blood glucose level in normal rats and interaction with the oral anti-diabetic drugs in Alloxan-induced diabetic rats. Method: The rats were classified into nine groups (n = 6).The Group I –II were normal and Group III –IX were diabetic. The experimental diabetes in rats was induced by intra-peritoneal injection of Alloxan monohydrate (135 mg/kg body ...

BACKGROUND India is considered as the diabetic capital of the world. The study of plants having antihyperglycemic and hypolipidemic activities may give a new approach in the treatment of diabetes mellitus. OBJECTIVE The study was intended to evaluate the antihyperglycemic and hypolipidemic activity of aqueous extract of leaves of Carica papaya Linn. (AECPL) in alloxan-induced diabetic albino ...