The murine monoclonal antibody R8B12 recognizes the C-terminal region (residues 563-740) of the A2 subunit of factor VIIIa [J Biol Chem 266: 1991; p. 20139], as judged by Western blotting. However, the location of the epitope within this region is not known. In the present study, we used affinity-directed mass spectrometry to map the epitope. A2 subunit was digested with trypsin or chymotrypsin...

The differential expression of microRNAs (miRNAs) in plasma of esophageal squamous cell carcinoma (ESCC) patients may serve as a diagnostic biomarker. A four-stage study was conducted to identify plasma miRNAs with potential in detecting ESCC. Exiqon panels (2 ESCC pools vs. 1 normal control (NC) pool) were applied in the screening phase to obtain miRNA profiles. The identified miRNAs were furt...

Is Associated With Enhanced Cerebral Vasodilatation to NADPH In Vivo Increased NADPH-Oxidase Activity and Nox4 Expression During Chronic Hypertension Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2004 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi: 10.1161/01.STR.0000112974.370...

Alexander Renz, Chronik der Stadt Heilbronn 1952-1957, bearb. und eingeleitet von Susanne Schlösser (Chronik Heilbronn, Bd. 7), (Stadtarchiv Heilbronn) 1996. 584 S. + Fototeil.

The evolution of cooperative behaviour is studied in the deterministic version of the Prisoners' Dilemma on a two-dimensional lattice. The payo parameter is set at the critical region 1:8 < b < 2:0 , where clusters of cooperators are formed in all spatial sizes. Using the factorial moments developed in particle and nuclear physics for the study of phase transition, the distribution of cooperato...

Katrin Lange, Gesellschaft und Kriminalität. Räuberbanden im 18. frühen 19. Jahrhundert (Europäische Hochschulschriften. Reihe 3, Bd. 584) Frankfurt/Main (Peter Lang) 1994. 282 S.

BACKGROUND Adjuvant chemotherapy (ACT) is known to improve survival in patients with early-stage non-small cell lung cancer. Herein, we describe chemotherapy regimens used, dose modifications, survival, and treatment-related toxicity in the general population. METHODS All cases of non-small cell lung cancer diagnosed in Ontario in the period 2004-2006 who underwent surgical resection (n = 335...