Larry L. Needham, a strong scientist and a staunch advocate for the use of exposure science in public health, passed away on 23 October 2010 after a 2‑year battle with renal cell carcinoma. He will be remem‑ bered as a scientist with great vision who had the ability to develop and sustain impact‑ ful research programs that provided a strong underpinning for furthering exposure science. These pr...

The poor prognosis associated with chaotic irregularity of the pulse was clearly known by most of ancient physicians. Perhaps the earliest description of atrial fibrillation is in Chinese, in The Yellow Emperors Classic of Internal Medicine, but in recorded history, William Harvey in 1628 was probably the first to describe ‘fibrillation of the auricles’ in animals. The first electrocardiographi...

John Merlie died suddenly and unexpectedly on May 27, 1995, of a heart attack. Hiswork on the regulation of neuromuscular synapse formation has had a major impact on the field, both in its breadth and in its accuracy. In fact, many feel that his most recent contributions and work soon to be published will be perhaps the most influential of his career. After earning a bachelor of science degree ...

The son of Ellen Key and Charles Hunt Morgan, T. H. Morgan was born on 25 September 1866 into a prominent family in Lexington, Kentucky. Morgan grew up exploring the environment around his childhood home and developed a special interest in fossils. As a young man, he spent a summer employed doing geological and biological fieldwork in the Kentucky mountains. He received his BS degree from the U...

CONTRIBUTIONS to the unemployment trust fund on 1945 wages are estimated at $1.05 billion, 1 or about 1 1 percent below the previous year's total of $1.17 billion. Although the end of the war in August 1945 caused taxable wages for 1945 to decline from *Prepared in the Program Division, Bureau of Employment Security. 1 Except for the discussion on page 16, the effect of war-risk provisions (inc...

Christopher John Ash was born on 5 January 1945 at Gorleston, a seaside town adjoining Great Yarmouth, Norfolk, England. He was an only child. His father, Kenneth William Ash, was the middle of three brothers. The elder brother was a Wing Commander in the Royal Air Force who worked on rocket research and the younger was a Captain in the Merchant Navy. Chris’s father was Borough Engineer at Redc...

We examined whether ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester (SNJ-1945), a new orally available calpain inhibitor, might reduce retinal cell death in vivo and/or in vitro. Retinal cell damage was induced in vivo in mice by intravitreal injection of N-methyl-d-aspartate (NMDA), and SNJ-1945 was intraperit...

Bacteria as a source of antibiotic materials have been the object of intensive study. Some of the bacteria more recently investigated for antibiotic properties have been Chromobacterium violaceum by Lichstein and Van de Sand (1945) and the Bacillus subtilis group by various workers, among whom may be mentioned Salle and Jann (1945), Johnson, Anker, and Meleney (1945), Olivier, De Saint Rat, and...