She later presented to the Samaritan Hospital, Belfast. The lesion had recurred and spontaneously resolved on three occasions, and she had had recurrent 'cold sores' on the lips, 'sores inside the mouth' and 'red eyes'. Her temperature was 38.3°C; there was ulceration of the buccal mucosa and a tender ulcer at the posterior fourchette. Eye examination was normal. Investigations showed a polymor...

The serology of treponemal disease has become simpler and more rational in recent years, mainly as a result of the widespread adoption of specific antibody tests and the use of monospecific fluorescent antibody procedures which give information about the immunoglobulin class of antibodies. A set of tests which has proved particularly useful in routine diagnosis is the following: quantitative TP...

Syphilis in pregnancy is a worrisome topic due to its fetal consequences. The diagnosis and management of such case might be intriguing when overlapped with Behçet’s disease, an inflammatory disease involving multiple organ systems. This presents 35-year-old pregnant female, known hypothyroidism, presenting at 33 weeks the emergency department Bahrain Defense Force (BDF) hospital vaginal leakin...

The incidence of acute hepatitis in syphilis patient is rare. First of all, our patient presented with hepatitis comorbid with thrombocytosis. To our knowledge, this is only the second report of syphilitic hepatitis with thrombocytosis. The 42-yr-old male complained of flu-like symptoms and skin eruptions on his palms and soles. Laboratory findings suggested an acute hepatitis and thrombocytosi...

Materials and methods A total of 270 patients attending the STD clinic of JIPMER, Pondicherry, India, were randomly included in the study irrespective of age and sex. A detailed examination was done to rule out any underlying STD. All the patients were screened for syphilis (VDRL), HIV infection (enzyme immunoassay for detection of antibodies to HIV-1, HIV-1 group 0 and HIV-2), HBV infection (r...

A 34 year old woman with 2 previous first trimester miscarriages and antenatal history of gestational diabetes well controlled on diet was initially booked at a private hospital for her antenatal follow up. Her first trimester screening was low risk for trisomy and screening scan at 20 weeks showed no fetal anomaly. Antenatal routine screening blood tests, including hepatitis B surface antigen ...

As early syphilis becomes more uncommon in the community, it will present frequently to the tertiary hospital as a diagnostic problem. Twenty patients with classic signs and symptoms of primary and secondary syphilis in whom the correct diagnosis was initially missed are presented. The importance of a routine admission Venereal Disease Research Laboratory test (VDRL) in making the correct diagn...