نتایج جستجو برای: vascular pathogenesis

تعداد نتایج: 330427  

2017
Benjamin J.F. Dean Stephanie G. Dakin Neal L. Millar Andrew J. Carr

Tendinopathy is a common clinical problem and has a significant disease burden attached, not only in terms of health care costs, but also for patients directly in terms of time off work and impact upon quality of life. Controversy surrounds the pathogenesis of tendinopathy, however the recent systematic analysis of the evidence has demonstrated that many of the claims of an absence of inflammat...

Journal: :BMB reports 2012
Qiong Xue Kathryn Miller-Jensen

Viruses have evolved to manipulate the host cell machinery for virus propagation, in part by interfering with the host cellular signaling network. Molecular studies of individual pathways have uncovered many viral host-protein targets; however, it is difficult to predict how viral perturbations will affect the signaling network as a whole. Systems biology approaches rely on multivariate, contex...

2014
Katie Haning Seung Hee Cho Lydia M. Contreras

Mycobacteria represent a class of powerful pathogens, including those causing tuberculosis and leprosy, which continue to be worldwide health challenges. In the last 20 years, an abundance of non-coding, small RNAs (sRNAs) have been discovered in model bacteria and gained significant attention as regulators of cellular responses, including pathogenesis. Naturally, a search in mycobacteria follo...

2015
Gregorio Alanis-Lobato

High-throughput detection of protein interactions has had a major impact in our understanding of the intricate molecular machinery underlying the living cell, and has permitted the construction of very large protein interactomes. The protein networks that are currently available are incomplete and a significant percentage of their interactions are false positives. Fortunately, the structural pr...

Journal: :journal of basic and clinical pathophysiology 2013
farshad roghani dehkordi arezou enteshari

abstract background and objective: vascular abnormality and dysfunction plays an important role in the pathogenesis of vascular disease in diabetic state. in this study, we aimed to investigate whether an in vitro exposure of endothelium-intact aortic rings to melissa officinalis (lemon balm, mo) aqueous extract could have a beneficial effect in rats with subchronic diabetes. materials and meth...

Journal: :iranian journal of radiation research 0
s.r. mahdavi department of medical physics, babol university of medical sciences, babol, iran a.r. nikoofar department of radiation oncology, iran university of medical sciences, tehran, iran h.r. mirzaee department of radiation oncology, shahid beheshti university of medical sciences, tehran, iran b. mofid department of radiation oncology, shahid beheshti university of medical sciences, tehran, iran r. mohammadi department of internal medicine, zanjan university of medical sciences, zanjan, iran

background: study of vascular and its secretory profile changes is an important issue in pathogenesis of radiation myelopathy. this paper reports the prostacyclin concentration changes after low-moderate doses of x-irradiation within a short period of time. materials and methods: cervical cords of wistar rats were irradiated to doses of 0.5, 1, 2, 4 and 6 gy x-rays. after 24 hours, 2 and 13 wee...

Journal: :basic and clinical cancer research 0
robab sheikhpour department of nursing, yazd branch, islamic azad university, yazd, iran/ hematology and oncology research center, shahid sadoughi university of medical science, yazd, iran

adiponectin is one of the most important members of adipokine family which is widely synthesized and secreted by adipose tissue. the action of adiponectin is via binding to main receptors. it has several actions including regulation of glucose level, lipid homeo­stasis and reproductive system. adiponectin can also influence vascular endothelium via preventing the migration of monocytes. the rol...

Journal: :bulletin of emergency and trauma 0
shahram bolandparvaz trauma research center, shiraz university of medical sciences, shiraz, iran. behzad ghaffari trauma research center, shiraz university of medical sciences, shiraz, iran. seyed mohsen mousavi trauma research center, shiraz university of medical sciences, shiraz, iran. shahram paydar trauma research center, shiraz university of medical sciences, shiraz, iran. hamid reza abbasi trauma research center, shiraz university of medical sciences, shiraz, iran.

objective: to evaluate the predictive value of some biochemical markers in the outcome of extremity vascular trauma. methods: this study comprised 30 patients with traumatic arterial injury and acute limb ischemia referred to namazi hospital affiliated with shiraz university of medical ssciences, over a period of 8 months, from sep 2009 to jul 2010. venous blood samples were drawn from distal i...

Journal: :The journal of medical investigation : JMI 2000
H Azuma

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder characterized by vascular dysplasia and hemorrhage. The pathogenesis regarding heterogeneity of vascular malformations in patients with HHT has been obscure, although it has become possible to partially explain the pathogenesis from the identification of two distinct genes, endoglin and ALK-1. Endoglin and ALK-1 are t...

Behrouz Gharesi-Fard, Elham Aflaki Eskandar Kamali-Sarvestani, Mohammad Ali Nazarinia Mohammad Reza Ataollahi Saeedeh Shenavandeh Zahra Habibagahi,

Background: The prevalence of anti-Neutrophil Cytoplasmic Antibodies (ANCAs) and anti-Cardiolipin Antibodies (anti-CL Ab) in Behcet’s Disease (BD) and also their roles in vascular involvement is controversial. Objective: To assess the prevalence of ANCAs and anti-CL Ab as well as their correlations with clinical manifestations in Iranian patients with BD. Methods: In this case/control study, th...

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