نتایج جستجو برای: urinary hippuric acid
تعداد نتایج: 844831 فیلتر نتایج به سال:
The purpose of this research was to determine mandelic, phenylglyoxylic, hippuric, o-, m- and p-methylhippuric acids, the six urinary metabolites of styrene, toluene and xylene by high performance liquid chromatography (HPLC). These metabolites were extracted in an acid medium, transferred into a basic solution and back extracted again using ethyl acetate, and the organic phase was evaporated t...
Studies upon the fate of the phenyl derivatives of fatty acids have thrown much light upon the possible transformation which the naturally occurring fatty acids may undergo in the course of their catabolism. Of these investigations of phenyl derivatives that upon phenylpropionic acid has been particularly illuminating. By injecting cats with the sodium salt of this acid, it has been possible to...
Studies upon the fate of the phenyl derivatives of fatty acids have thrown much light upon the possible transformation which the naturally occurring fatty acids may undergo in the course of their catabolism. Of these investigations of phenyl derivatives that upon phenylpropionic acid has been particularly illuminating. By injecting cats with the sodium salt of this acid, it has been possible to...
The beneficial health effects of cranberries have been attributed to their (poly)phenol content. Recent studies have investigated the absorption, metabolism and excretion of cranberry (poly)phenols; however, little is known about whether they follow a dose response in vivo at different levels of intake. An acute double-blind randomized controlled trial in 10 healthy men with cranberry juices co...
Organic anions accumulated in blood serum of patients with chronic renal failure were separated by a novel technique: closed-system capillary zone electrophoresis (CZE) in a pH6 carrier-electrolyte system. Hippuric acid (HA), p-hydroxyhippuric acid, and uric acid were identified by their co-elution with standards prepared in ultrafiltered normal serum and by comparison with the corresponding ul...
This work describes a new extraction method with hollow-fiber liquid-phase microextraction based on facilitated pH gradient transport for analyzing hippuric acid and mandelic acid in aqueous samples. The factors affecting the metabolites extraction were optimized as follows: the volume of sample solution was 10 mL with pH 2 containing 0.5 mol·L-1 sodium chloride, liquid membrane containing 1-oc...
Endothelial Cell Dysfunction (ECD) is a recognized harbinger of a host of chronic cardiovascular diseases. Using a mouse model of ECD triggered by treatment with L-Nω-methylarginine (L-NMMA), we previously demonstrated that renal microvasculature displays a perturbed protein profile, including diminished expression of two key enzymes of the Krebs cycle associated with a Warburg-type suppression...
Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and as insecticides for the management of insect pests. We show here that relatively simple ground state analogs of the PHM substrate hippuric...
These studies were undertaken in order to determine the clinical value of the sodium benzoate test of renal function as proposed by Kingsbury and Swanson (27). Hippuric acid has claimed the attention of physiologic chemists and pathologists for many years (40). The basis of this interest lies in the generally accepted fact of its formation in the body by the conjugation of benzoic acid, or its ...
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