Thyrotropin (TSH) secreting pituitary adenomas (TSH-omas) account for < 1% of all pituitary adenomas and are a rare cause of hyperthyroidism. The diagnosis is often made at the stage of macroadenoma because of the aggressive nature of the tumor and due to the fact that patients are mistakenly treated for more common primary hyperthyroidism for a long time. First line therapy is transsphenoidal ...

The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery. A total of 28 patients were studied. The preoperative pulsatile secretion of ACTH and cortisol was assessed by sampling blood at 20-min intervals over 24 h. T...

Cushing's disease is a condition of hypercortisolism caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma. While rare, it is associated with significant morbidity and mortality, which suggests that early and aggressive intervention is required. The primary, definitive therapy for patients with Cushing's disease in the majority of patients is pituitary surgery, generally p...

Intrasellar arachnoid cysts represent around 1% of all selar lesions. Generally, patients are asymptomatic and when they exhibit visual and/or hormonal disturbances, the indication for surgery is prompted. A 51-year-old woman with a known purely intrasellar cyst diagnosed 23 years prior to presentation, evolved gradual campimetric evaluation. Magnetic resonance imaging showed significant growth...

CONTEXT Cushing's syndrome (CS) is associated with symptoms that may impair health-related quality of life (HRQL). METHODS We used the short-form 36 survey to evaluate HRQL in 23 patients with Cushing's disease before and after transsphenoidal surgery (age, 42.7 +/- 12.0 yr; 19 women and four men) and in a cross-section of 343 CS patients (age, 48.2 +/- 14.1 yr; 265 women and 78 men) in remis...

Cushing's disease or pituitary-dependent hyperadrenocorticism (PDH) is common in dogs and rare in cats. PDH is caused by a pituitary tumor producing adrenocorticotropin (ACTH). Pituitary imaging with computed tomography (CT) or magnetic resonance imaging (MRI) is required to assess the size and location of the pituitary adenoma in relation to the surgical landmarks. In a specialized veterinary ...

Objective : We aimed to examine the effect of different intervals end tidal CO2 ( etCO2 ) values on hemodynamics and surgery in endoscopic endonasal transsphenoidal pituitary surgery. Material Methods: Two groups were evaluated retrospectively according maximum at time sellar resection. Group 1: 21 patients, etCO 2 =25-37 mmHg 2: 2=38-50 mmHg. The demographic characteristics, mean arterial pres...

Introduction: This case report aimed to highlight the prominence of considering Cushing's disease in differential diagnosis severe hypokalemia and metabolic alkalosis.&#x0D; Case Report: A 63-year-old woman who admitted emergency room Bezmialem Vakif University Hospital, Istanbul with fatigue weakness extremities. Biochemistry results indicated (potassium=1.2 mmol/L) alkalosis (pH= 7.83) based ...