Cytochromes c are typically characterized by the covalent attachment of haem to polypeptide through two thioether bonds with the cysteine residues of a Cys-Xaa-Xaa-Cys-His peptide motif. In many Gram-negative bacteria, the haem is attached to the polypeptide by the periplasmically functioning cytochrome c maturation (Ccm) proteins. Exceptionally, Hydrogenobacter thermophilus cytochrome c552 can...

Oxidation of thioester substrates in the medium-chain acyl-CoA dehydrogenase involves alpha-proton abstraction by the catalytic base, Glu376, with transfer of a beta-hydride equivalent to the flavin prosthetic group. Polarization of bound acyl-CoA derivatives by the recombinant human liver enzyme has been studied with 4-thia-trans-2-enoyl-CoA analogues. Polarization is maximal at low pH, with a...

The synthesis and analytical applications of the new heterocyclic ligand are described. The complexation reaction of the ligand with some cations was studied in aqueous methanol at room temperature using the spectrophotometric method. Results revealed that only the absorption spectra of the Fe (III)–ligand complex show a high redshift of the absorption maximum in the aqueous methanol soluti...

A series of gold(I) and gold(III) complexes with N-heterocyclic carbene ligands functionalized a pendant thioether group (NHC-SR) was synthesized straightforward procedures characterized in solution NMR spectroscopy ESI-MS spectrometry, as well the solid state by means single crystal X-ray diffraction analysis. Selected experimental aspects were rationalized through relativistic DFT calculation...

This work describes the tribochemical evaluation of vegetable oil based antiwear additive obtained through chemical modification. The Sulfur was incorporated using a chemical reaction of epoxidized vegetable oil and common thiols, resulting in formation of a hydroxy thioether derivative of vegetable oils. The synthesis retains the vegetable oil structure, eliminates poly-unsaturation in the mol...